Knowledge Library

Outsourcing Drug Discovery and Development: Considerations For Emerging Biopharma Companies

Resource Type: White Paper
Resource Topic: Candidate Selection, Discovery Chemistry, DRUG DISCOVERY AND INNOVATION, Hit Finding, Hit-to-Lead, Lead Optimization, Target Identification and Validation

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Targeted Protein Degradation Platform

Integrated Services BIOLOGY & PHARMACOLOGY BINARY/TERNARY COMPLEX FORMATION Biochemical & Biophysical Assays Biochemical binding assay Cellular Assays TARGET UBIQUITINATION & DEGRADATION In vitro Assays-Target ubiquitination Target degradation assay PK/PD Animal Disease Model Evaluation CHEMISTRY Specific virtual library design Compound synthesis Conjugation and all type of custom syntheses from milligram to kilogram scale Purification and analytical …Read More >

Resource Type: Brochure
Resource Topic: Biochemical Assays, Biophysical Assays, Cell-based Assays, Discovery Chemistry, Hit-to-Lead, Lead Optimization, Small Molecules, Targeted Protein Degradation

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Discovery Chemistry Outsourcing Services

Global Leader in Discovery Chemistry Outsourcing Services Based on FTE (Full Time Equivalent) Model | Customization to Client’s Synthetic Chemistry with high productivity, quality, speed, and reliability Project Management:  we manage project timelines and compound flow Medicinal Chemistry: we provide compound design and project management Integrated Projects from targets to hits to leads to preclinical …Read More >

Resource Type: Brochure
Resource Topic: Candidate Selection, Chemical Biology and Proteomics, Discovery Chemistry, Hit-to-Lead, Lead Optimization, Mass Spectrometry-based Assays, Quantum Mechanics, Small Molecules

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Translational Oncology

Biomarker discovery Mouse clinical trial 61 PDX-derived primary cancer cell lines Drug-resistant xenograft models Combination therapy platform including radiation World leading genome sequencing and bioinformatics capability

Resource Type: Brochure
Resource Topic: Biomarkers, Candidate Selection, Cell-based Assays, Cells and Protein Science, Chemical Biology and Proteomics, Lead Optimization, Oncology, Phenotypic Assays, Tumor Models

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Patient-Derived Xenograft (PDX) Tumor Models

One of the largest collection of Patient-Derived Xenograft (PDX) Tumor Models in Asia with gene expression/mutation profiling 1200 PDX models Collection of PDX models prevalent in Asia 800+ PDX models with genetic profiling Searchable online database with mobile APP Integrated online database for PDX, CDX & Syngeneic tumor models with mobile App PDX with oncogene …Read More >

Resource Type: Brochure
Resource Topic: Biomarkers, in vivo Pharmacology, Lead Optimization, Tumor Models

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Immuno-Oncology Services

Immuno-oncology Platform An outstanding platform to enable cancer immunotherapy with one stop service: Immunological function assessment TIL analysis – Flowcytometry, Multiplex IF and Cytex Animal models – Syngeneic and humanized models Immune profiling by NGS – Single Cell RNAseq, Mutation burden and TCR/BCR repertoire Clinical biomarker services – CAP certification and GCP compliance

Resource Type: Brochure
Resource Topic: Antibodies, Autoimmune and Inflammatory Diseases, Biomarkers, Cell-based Assays, Cells and Protein Science, Hit-to-Lead, Immunology, in vivo Pharmacology, Lead Optimization, Oncology, Phenotypic Assays, Target Identification and Validation, Target-Specific Assays, Tumor Models

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Cell Line-Derived Xenograft (CDX) Tumor Models

A large collection of cell line-derived xenograft (CDX) tumor models 215 validated models, SOC data available World leading imaging based orthotopic/metastatic CDX platform 28 models covering 16 tumor types

Resource Type: Brochure
Resource Topic: in vivo Pharmacology, Lead Optimization, Oncology, Oncolytic Viruses, Small Molecules, Target Identification and Validation, Tumor Models

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WuXi Oncology and Immuno-Oncology Services

Integrated Oncology and Immuno-oncology Platform to Enable Translational Science from Drug Discovery to Clinical Biomarker Oncology Services CRISPR/Cas9 Gene Editing In Vitro Assay and HTS Tumor models Tumor Cell Panel and Screening Immunology and Immuno-oncology Platform Clinical Biomarker Immunology Services Ligand-receptor binding assays Cellular functional assays Assays for innate immunity pathways: macrophage, MDSC, NK, DC, …Read More >

Resource Type: Brochure
Resource Topic: Antibodies, Biochemical Assays, Biomarkers, Cell-based Assays, Cells and Protein Science, Chemical Biology and Proteomics, Gene Therapies, High-throughput screening (HTS), Hit-to-Lead, Immunology, in vitro biology, in vivo Pharmacology, Lead Optimization, Oncology, Screening Libraries, Small Molecules, Target Identification and Validation, Target-Specific Assays, Targeted Protein Degradation, Tumor Models

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Virology and Viral Vector Platforms

WuXi virology platforms: Immunology, Anti viral, Viral Vector, Oligo-nucleotide, Clinical and Immunology in vitro screening and profiling in vivo efficacy clinical virology Liver-specific viruses | Respiratory viruses | Herpes viruses | Other viruses

Resource Type: Brochure
Resource Topic: Biochemical Assays, Biomarkers, Candidate Selection, CAR-T Cell, Cell-based Assays, Cells and Protein Science, in vivo Pharmacology, in vivo Toxicology, Infectious Diseases, Lead Optimization, Oncolytic Viruses, Phenotypic Assays, Safety and Early Toxicity

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Resource Topics
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