Integrated Platforms

Integrated Drug Discovery and Research Platform

We offer comprehensive end-to-end solutions for creating, identifying, and supporting preclinical candidates, from discovery to development, with our integrated chemistry and biology research platform. Our experts provide integrated solutions to global pharma and biotech for challenging targets. We deliver synthetic and medicinal chemistry solutions,  and biology services for creating, identifying, and supporting preclinical candidates, from discovery to development.

We work collaboratively to rapidly advance programs from target validation to preclinical selection and beyond through a comprehensive discovery and technology platform, peer-recognized scientific leadership and expertise in oncology, immunology, infectious disease, neurosciences, fibrosis, cardiovascular and metabolic diseases. Learn more

Integrated Platform

Research and Developemnt

Biological Science

Discovery Chemistry

Research and Developemnt

Target-to-hit

Biological Science

  • Target validation, CRISPR
  • Protein production
  • HTS, FBDD
  • X-ray crystallography
  • Biophysical analytics
  • CADD

Discovery Chemistry

  • Reference compounds
  • Arrays, libraries, DELs
  • Unique scaffolds, building blocks
  • DNA Encoded Libraries
  • Customized screening decks

Research and Developemnt

Hit-to-lead

Biological Science

  • In vitro efficacy & MoA
  • In vivo efficacy
  • PK/PD analysis

Discovery Chemistry

  • SAR generation
  • Molecule design
  • Building blocks

Research and Developemnt

Lead optimization

Biological Science

  • In vitro SAR support
  • Selectivity panel
  • Cell panel
  • In vivo target engagement
  • In vivo pharmacology

Discovery Chemistry

  • Optimization of hits and leads
  • Data interpretation
  • Candidate selection

Research and Developemnt

Pre-clinical

Biological Science

  • hERG, other safety profiling services
  • Ligand binding
  • Receptor profiling
  • Additional in vitro and in vivo characterization

Discovery Chemistry

  • Scale up of candidates for preclinical studies
  • Synthetic optimization of candidates
  • Metabolic and impurity identification synthesis

Research and Developemnt

Clinical I - III

Biological Science

  • PDX
  • Tumor TILs
  • Biomarkers
  • CAP-certified FACS, pathology, molecular testinh