Integrated Platforms
Integrated Drug Discovery and Research Platform
We offer comprehensive end-to-end solutions for creating, identifying, and supporting preclinical candidates, from discovery to development, with our integrated chemistry and biology research platform. Our experts provide integrated solutions to global pharma and biotech for challenging targets. We deliver synthetic and medicinal chemistry solutions, and biology services for creating, identifying, and supporting preclinical candidates, from discovery to development.
We work collaboratively to rapidly advance programs from target validation to preclinical selection and beyond through a comprehensive discovery and technology platform, peer-recognized scientific leadership and expertise in oncology, immunology, infectious disease, neurosciences, fibrosis, cardiovascular and metabolic diseases. Learn more
Integrated Platform
Research and Developemnt
Biological Science
Discovery Chemistry
Research and Developemnt
Target-to-hit
Biological Science
- Target validation
- Protein production
- HTS, FBDD
- X-ray crystallography
- Biophysical analytics
- CADD
Discovery Chemistry
- Reference compounds
- Arrays, libraries, DELs
- Unique scaffolds, building blocks
- DNA Encoded Libraries
- Customized screening decks
Research and Developemnt
Hit-to-lead
Biological Science
- In vitro efficacy & MoA
- In vivo efficacy
- PK/PD analysis
Discovery Chemistry
- SAR generation
- Molecule design
- Building blocks
Research and Developemnt
Lead optimization
Biological Science
- In vitro SAR support
- Selectivity panel
- Cell panel
- In vivo target engagement
- In vivo pharmacology
Discovery Chemistry
- Optimization of hits and leads
- Data interpretation
- Candidate selection
Research and Developemnt
Pre-clinical
Biological Science
- hERG, other safety profiling services
- Ligand binding
- Receptor profiling
- Additional in vitro and in vivo characterization
Discovery Chemistry
- Scale up of candidates for preclinical studies
- Synthetic optimization of candidates
- Metabolic and impurity identification synthesis
Research and Developemnt
Clinical I - III
Biological Science
- PDX
- Tumor TILs
- Biomarkers
- CAP-certified FACS, pathology, molecular testinh
