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Advances in Covalent Drug Discovery Technologies

From Aspirin to Targeting KRAS: These Technologies Are Redrawing the Frontiers of Drug Discovery From aspirin to modern KRAS inhibitors, covalent drugs have evolved from...

How WuXi AppTec’s San Diego Site Connects Biology and Chemistry

From Discovery to the Clinic: Drug discovery does not move forward through isolated steps. A promising biological insight must be translated into validated assays, high-quality...

From 40 Billion Molecules to Druggable Potential

Targeted protein degradation (TPD) is moving beyond traditional E3 ligases such as CRBN and VHL, with growing interest in identifying novel E3 ligases. To support...