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Advances in Covalent Drug Discovery Technologies
From Aspirin to Targeting KRAS: These Technologies Are Redrawing the Frontiers of Drug Discovery From aspirin to modern KRAS inhibitors, covalent drugs have evolved from...
Continue ReadingHow WuXi AppTec’s San Diego Site Connects Biology and Chemistry
From Discovery to the Clinic: Drug discovery does not move forward through isolated steps. A promising biological insight must be translated into validated assays, high-quality...
Continue ReadingFrom 40 Billion Molecules to Druggable Potential
Targeted protein degradation (TPD) is moving beyond traditional E3 ligases such as CRBN and VHL, with growing interest in identifying novel E3 ligases. To support...
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Advancing Metabolic Disease Drug Development: Integrated Preclinical Strategies from Discovery to IND-Enabling Studies
September 29, 2026
Metabolic drug development is evolving rapidly with advances in incretin biology and an increasingly complex therapeutic landscape. Moving promising candidates toward the clinic requires more...
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