Comprehensive Platform and Services

Our Oncology & Immunology teams can support all of your research needs, ranging from target discovery to in vitro/in vivo pharmacology, translational research, and clinical biomarker testing to accelerate projects focused on cancer, autoimmune diseases, and rare genetic diseases (RGD).

We have established a disease model library comprised of over 2,000 animal models representing cancer, autoimmune diseases, and rare genetic diseases:

  • Tumor model libraries of human cancer cell line-derived xenograft (CDX) models, patient-derived xenograft (PDX) models, drug-resistant models and metastasis models.
  • Immuno-oncology libraries of murine syngeneic tumor models, humanized mice by adoptive and KO/KI approaches
  • Sub-libraries of autoimmune and inflammation models
  • Collection of RGD models via genetic engineering

We have a world-class platform for CRISPR/Cas9 mediated in vitro and in vivo screens for target identification and validation, and we have also established a comprehensive Immuno-Oncology translational platform:

  • Biomarker discovery platform with state of art technology including flow cytometry, NanoString, scRNAseq, RNAscope and multiplex IF;
  • CAP certified lab for clinical pathology and flow cytometry with over 200 clinical validated biomarkers to support clinical drug development.
  • Large animal (NHP, canine, swine) based translational research platform with state-of-art facility, comprehensive biomarker research and human correlation capability

One-stop services platform for rare genetic diseases, from animal model creation to pre-clinical testing.

Rich experience in IND-enabling pharmacology studies for both FDA and NMPA filings, as either stand-alone or as integrated drug discovery programs.

Immunology End-to-end services and solutions to enable cancer drug discovery Discovery and clinical biomarker services by pathology and flow-cytometry Generation of cell lines with CRISPR-mediated gene knockout, mutation knocking A large collection andtumors model for small& large molecule drugdrug discovery Tumor Models CRISPR/Cas9 Biomarker

Capabilities at a Glance


Resources at a Glance

  • 700+ scientists with operations at multiple locations
  • AAALAC credited SPF animal facility with over 30,000 IVC-cages
  • BSL2 in vitro labs
  • ABSL2 vivarium
  • CAP certified clinical pathology and FACS lab

Related Resources View All

Drug Resistant Models

Resource Type: Brochure

Cancer Pharmacology Services

Resource Type: Brochure

Large Animal Disease Models

Resource Type: Brochure

Immune Profiling Platform

Resource Type: Brochure

Tumor Cell Panel | Screening Services

Resource Type: Brochure

Clinical Biomarkers

Resource Type: Brochure

Rare Genetic Disease Platform

Resource Type: Brochure

Target Identification and Validation

Resource Type: Brochure

Immunology Assays

Resource Type: Brochure

Orthotopic and Metastasis Syngeneic Models

Resource Type: Latest Science Presentation

DLL3-Related PDX Models

Resource Type: Latest Science Presentation

c-MET Related In Vivo Models

Resource Type: Latest Science Presentation

BRAF-Related In Vivo Models

Resource Type: Latest Science Presentation

Xenograft and Syngeneic Tumor Models in Rats

Resource Type: Latest Science Presentation

KRAS-related Genetically Engineered Cell Lines and In Vivo Models

Resource Type: Latest Science Presentation

Targeted Protein Degradation

Resource Type: Brochure Latest Science

In Vitro Imaging Services

Resource Type: Latest Science Presentation

CDK4/6 Inhibitor Resistant Breast Cancer Models

Resource Type: Latest Science Presentation

How Does It Work? | Aptamers

Resource Type: Video

How Does It Work? | Peptibodies

Resource Type: Video

How Does It Work? | RNAi

Resource Type: Video

WuXi AppTec Discovery Services

Resource Type: Brochure

WuXi Biology GPCR Cell Lines and Assays

Resource Type: Brochure

CAR-T TCR-T

Resource Type: Brochure

Antibody and Protein Preparation Services

Resource Type: Brochure Latest Science

Translational Oncology

Resource Type: Brochure

Immuno-Oncology Services

Resource Type: Brochure

CRISPR/Cas9 Gene Editing

Resource Type: Brochure