Knowledge Library

OncoWuXi Express: Animal Models of Parkinson’s Disease

Introduction: OncoWuXi Express will continue to keep you informed about updates to our online pharmacology model database (OncoWuXi Database), as well as our recent progress in preclinical research. In this issue, we showcase animal models related to Parkinson’s disease. https://onco.wuxiapptec.com Introduction Pathogenesis of Parkinson’s Disease Parkinson’s Disease (PD) is a widely prevalent neurodegenerative disorder globally. …Read More >

Resource Type: Article, Blog
Resource Topic: Central Nervous System & Pain, in vivo Pharmacology

VIEW

Innovative R&D Strategies for Peptide Drugs in Obesity Treatment

Introduction: Obesity has emerged as a pressing global public health issue, with its prevalence escalating at an unprecedented rate across the world. Body Mass Index (BMI) is a commonly used indicator to assess the degree of obesity. According to the World Obesity Atlas 2025, by 2030, over 2.9 billion adults globally will have a high …Read More >

Resource Type: Article, Blog
Resource Topic: in vivo Pharmacology, Metabolic Diseases, Peptides

VIEW

Endometriosis: Animal Models as Tools to Accelerate New Therapeutics

Introduction Endometriosis is a common gynecological condition that significantly impacts the health of women of reproductive age worldwide. Approximately 10% of reproductive-aged women and girls are affected by this condition [1]. As a complex estrogen-dependent disease, endometriosis can onset from menarche and persist until menopause. There is currently no cure; treatments primarily aim to alleviate …Read More >

Resource Type: Article, Blog
Resource Topic: Autoimmune and Inflammatory Diseases, in vivo Pharmacology

VIEW

AACR 2025 Posters: Sneak Peek

From April 25 to 30, 2025, the annual meeting of the American Association for Cancer Research (AACR), one of the largest and longest-standing cancer research conferences in the world, will be held in Chicago. At this year’s AACR meeting, WuXi Biology has been selected to present several posters detailing latest scientific insights, covering a range …Read More >

Resource Type: Article, Blog
Resource Topic: Antibody Drug Conjugate, Oligonucleotides, Oncology, Tumor Models

VIEW

Advancements in Membranous Nephropathy

From Pathogenesis to Therapeutic Innovations Introduction: Membranous nephropathy (MN) has received particular attention among autoimmune kidney disease due to its distinct pathophysiology and clinical manifestations. Unlike other autoimmune nephropathies, MN is primarily driven by pathogenic autoantibodies that activate immune cells, leading to oxidative stress and inflammatory responses that compromise the glomerular filtration barrier [1, 2]. …Read More >

Resource Type: Article, Blog
Resource Topic: Autoimmune and Inflammatory Diseases

VIEW

Emerging Role of GLP-1 Receptor Agonists for the Treatment of MASH

Abstract: Emerging as a major global health concern, metabolic dysfunction-associated steatohepatitis (MASH) is closely linked to obesity, type 2 diabetes, and other metabolic disorders. Advances in metabolic research have positioned glucagon-like peptide-1 receptor agonists (GLP-1 RAs) as a promising therapeutic option for MASH, extending their use beyond diabetes and obesity management. This article examines the …Read More >

Resource Type: Article, Blog
Resource Topic: in vivo Pharmacology, Liver Diseases, Metabolic Diseases, NASH

VIEW

International Women’s Day: Safeguarding Women’s Health Across the Lifespan with the Power of Science

Introduction In recognition of International Women’s Day, we spotlight women’s health—a continuously evolving global healthcare issue. The year 2025 marks the 30th anniversary of the United Nations Fourth World Conference on Women, where the landmark Beijing Declaration was adopted. This pivotal document systematically outlined an action framework for advocating women’s rights, with a particular emphasis …Read More >

Resource Type: Article, Blog
Resource Topic: Autoimmune and Inflammatory Diseases, Cardiovascular & Metabolic Diseases, in vivo Pharmacology

VIEW

Women’s Health: Innovative Medications for Menopause

Introduction: Women spend about one-third of their lives in menopause or post-menopause, a period that marks the gradual decline of their reproductive capabilities [1, 2]. Menopause typically begins between the ages of 45 and 55 and is marked by 12 consecutive months without menstruation. Menopausal syndrome refers to a series of physiological and psychological symptoms …Read More >

Resource Type: Article, Blog
Resource Topic: Autoimmune and Inflammatory Diseases, Cardiovascular & Metabolic Diseases, in vivo Pharmacology

VIEW

Comprehensive Fibrosis Drug Development Platform

Introduction: Fibrosis is a pathological process characterized by the excessive deposition of extracellular matrix (ECM) within an organ, leading to significant damage to its structure and function, which can potentially impact multiple organs such as the lungs, liver, heart, kidneys, and skin (Fig.1). Notable examples of fibrotic diseases include idiopathic pulmonary fibrosis (IPF), liver cirrhosis, …Read More >

Resource Type: Article, Blog
Resource Topic: Autoimmune and Inflammatory Diseases, in vivo Pharmacology

VIEW


Resource Topics
× peptide, amino acid

Contact An Expert Today!