Targeted Protein Degradation Platform PROTAC

PROTAC BIOLOGY & PHARMACOLOGY

BINARY/TERNARY COMPLEX FORMATION

  • Biochemical & Biophysical Assays
  • Biochemical binding assay
  • Cellular Assays

TARGET UBIQUITINATION & DEGRADATION

  • In vitro Assays-Target ubiquitination
  • Target degradation assay
  • PK/PD
  • Animal Disease Model Evaluation

PROTAC CHEMISTRY

  • PROTAC specific virtual library design
  • Compound synthesis
  • Conjugation and all type of custom syntheses from milligram to kilogram scale
  • Purification and analytical support on PROTAC featured compounds


HDB - PROTAC

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