Targeted Protein Degradation Platform PROTAC
PROTAC BIOLOGY & PHARMACOLOGY
BINARY/TERNARY COMPLEX FORMATION
- Biochemical & Biophysical Assays
- Biochemical binding assay
- Cellular Assays
TARGET UBIQUITINATION & DEGRADATION
- In vitro Assays-Target ubiquitination
- Target degradation assay
- PK/PD
- Animal Disease Model Evaluation
PROTAC CHEMISTRY
- PROTAC specific virtual library design
- Compound synthesis
- Conjugation and all type of custom syntheses from milligram to kilogram scale
- Purification and analytical support on PROTAC featured compounds
HDB - PROTAC
Resource Topics
- Biophysic
- Cancer Research
- Discovery Chemistry
- Drug Discovery
- Hit Finding and Screening Services
- in vitro biology
- in vivo Pharmacology
- Infectious Diseases
- Liver Diseases
- Oncology & Immuno-oncology
- Protein Services
- Structural Biology
- Target Validation
- Technologies
- Therapeutic Modalities