Targeted Protein Degradation Platform PROTAC
PROTAC BIOLOGY & PHARMACOLOGY
BINARY/TERNARY COMPLEX FORMATION
- Biochemical & Biophysical Assays
- Biochemical binding assay
- Cellular Assays
TARGET UBIQUITINATION & DEGRADATION
- In vitro Assays-Target ubiquitination
- Target degradation assay
- PK/PD
- Animal Disease Model Evaluation
PROTAC CHEMISTRY
- PROTAC specific virtual library design
- Compound synthesis
- Conjugation and all type of custom syntheses from milligram to kilogram scale
- Purification and analytical support on PROTAC featured compounds
HDB - PROTAC