Leveraging multiple technologies to enable rapid and successful hit finding

WuXi AppTec provides a range of different hit finding techniques which can be applied either individually or in parallel, depending on the target, to find tractable hit matter with the highest chance of being optimized into a drug.

Fully integrated hit finding campaigns with medicinal chemistry, in vitro biology and ADME for lead optimization Highthroughput Screening HTS Affinity Selection Mass Spectrometry (ASMS) Screening DNA-Encoded Library (DEL) Fragment-based Drug Discovery Virtual Screening (CADD)

Across all these platforms, the process of identifying the most appropriate hit finding methodologies is enabled by experience sharing between our own seasoned drug hunters and the clients’ expertise, resulting in carefully constructed proposals with comprehensive, fully costed, hit finding scenarios.