Discovery Chemistry
Research Services
Through our comprehensive platform of specialty and medicinal chemistry services, we provide end-to-end solutions to global pharma and biotech customers for supporting the identification and optimization of lead compounds, to accelerate the selection of preclinical candidates.
Capabilities and Capacity

20+ years’ experience

7 research sites worldwide

1300+ global clients
- 20 of global top 20 pharmaceutical companies
- 516 clients have FTE collaboration
- 27 clients with 50+ FTE team including:13 clients with 100+ FTE teams
- 458 clients with >5 years’ collaboration including: 75 clients with >10 years’ collaboration
- FFS collaboration covers 1,200+ customers from mg to kg scale synthesis
- 11,000+ Regular FFS Projects per year, > 95% on time delivery rate
- 1,200+ DPC (Discovery Process Chemistry) projects per year
- FFS is well recognized by customers with high Net Promotion Score (NPS) over 85
- View our integrated platform of chemistry services
Specialty Chemistry

Library

Carbohydrate Chemistry

Nucleoside/tides

Macrocyclic Chemistry

Boron Chemistry

Fluorescent Bio-probe and Labeling

Steroids Chemistry

Fluorine Chemistry

Lipids

Isotope Labeling

Discovery Process Chemistry

Impurity Profiling
Technology Platform

Computer-aided Drug Design

Quantum Mechanics

PROTAC®

Flow Chemistry

Electrochemistry

Photoredox Chemistry

Late Stage Functionalization

Biotransformation

Crystallization Platform

Reaction Condition Screening

Catalyst Screening
Additional Services

Analysis & Purification

Catalog & Reagent

Compound Management

LabNetwork
Custom Synthesis
- More than 3,400 dedicated synthetic chemists provide services in custom synthesis;
- Full synthetic capability in a variety of scales, a broad spectrum of chemical matters, a wide range of complexity, and different type of customers;
- Deliver >40,000 compounds per year from mg to kg scale;
- >95% on time delivery rate for the known target compounds, and >90% for the unknown targets;
- Quick turnaround time supported by analytical, purification, WuXi AppTec catalog as well as logistic department;
- A dedicated group of experts in route design and trouble shooting in organic synthesis.
- View our webinar to learn how parallel medicinal chemistry and high throughput experimentation (combined with machine learning) can provide a more focused approach to target molecules
- View our publication: Discovery and preclinical profile of LX-039, a novel indole-based oral selective estrogen receptor degrader (SERD)
Targeted Covalent Inhibitor Discovery Chemistry Platform
>900 Discovery chemists, with strong experiences in targeted covalent inhibitor synthesis
>48,000 Covalent compounds successfully delivered
>12 Types of warheads, including acrylamide, chloroacetamide, 2-chloropropionamide and vinyl sulfone
View our talk at DDC 2023 entitled: “Biophysical and Structural Biology Methods Enable Fragment-based Covalent Ligand Discovery of Human BTK

Synthetic Chemistry
Medicinal Chemistry
Process Chemistry
Delivering synthetic and medicinal chemistry solutions to global pharma and biotech customers for creating, identifying, and supporting preclinical candidates, from discovery to development, with our FTE Chemistry Services.

We have over 4,500 synthetic and medicinal chemists and over 430 managers with over 19 years of experience serving global pharma and biotech customers. We have a strong synthetic and medicinal chemistry platform including technology platform, specialty chemistry and integrated discovery.