Knowledge Library

Quality Control for DNA-Encoded One-Bead-One-Compound (OBOC) Libraries

Resource Type: Presentation Video
Resource Topic: Biochemical Assays Biophysical Assays Chemical Biology and Proteomics DNA-Encoded Library (DEL) Hit Finding in vitro biology Phenotypic Assays Screening Libraries Small Molecules Target Identification and Validation

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Discovery of RNA Targeting Small Molecule Using DNA-Encoded Library Technology

Resource Type: Presentation Video
Resource Topic: DNA-Encoded Library (DEL) Hit Finding

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Drug Discovery: Screening Approaches for Rapid Assessment of Target Tractability

Resource Type: Webinar
Resource Topic: Biophysical Assays DNA-Encoded Library (DEL) Fragment-Based Drug Discovery Hit Finding Hit-to-Lead Screening Libraries Small Molecules Target Identification and Validation Target-Specific Assays

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Optimizing Drug Pipelines With Biophysical Methods

Download our whitepaper on how using biophysical techniques can enhance and streamline processes throughout the drug discovery and validation cycle. Discover fresh opportunities to characterize challenging drug targets, examine biophysical screening methods, and look toward what’s next for biophysical methods in drug discovery.

Resource Type: White Paper
Resource Topic: Biochemical Assays Biophysical Assays Discovery Chemistry DNA-Encoded Library (DEL) Fragment-Based Drug Discovery Hit Finding Hit-to-Lead Mass Spectrometry-based Assays Screening Libraries Small Molecules Structural Biology Target Identification and Validation Target-Specific Assays

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Structure determination: comparison of methods

WuXi AppTec offers comprehensive structural generation solutions for today´s challenging targets. Our experts provide insights and data to support hit finding through to lead optimization.

Resource Type: Brochure Infographic
Resource Topic: Biophysical Assays Cells and Protein Science Hit Finding Hit-to-Lead Lead Optimization Structural Biology Target Identification and Validation

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WuXi Discovery Services Newsletter: June 2021

Resource Type: Newsletter
Resource Topic: DNA-Encoded Library (DEL) Hit Finding

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One-Stop Target-to-Hit Solutions

WuXi AppTec  | Target-to-Hit Solutions Protein Production  | All Target Classes and Challenging Proteins Biophysical & Biochemical Platforms |  Ready-To-Go Assay for Broad Range of Drug Targets Structural Biology Platforms Covalent and non-covalent fragment libraries & Screening

Resource Type: Brochure
Resource Topic: Biochemical Assays Biophysical Assays Cells and Protein Science Chemical Biology and Proteomics Discovery Chemistry DNA-Encoded Library (DEL) Fragment-Based Drug Discovery Hit Finding Hit-to-Lead Lead Optimization Mass Spectrometry-based Assays Screening Libraries Small Molecules Structural Biology Target Identification and Validation

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DELpro: A New Method of Hit Discovery

DNA-Encoded Library (DEL) technology involves a novel affinity selection process that integrates chemistry, biology, bioinformatics and computational chemistry to facilitate a rapid drug discovery process, allowing access to more chemical space with lower cost. In contrast to high throughput screening, DEL requires a very small amount of target protein and minimum assay development. More importantly, …Read More >

Resource Type: Brochure
Resource Topic: Chemical Biology and Proteomics DNA-Encoded Library (DEL) Hit Finding Screening Libraries Small Molecules Target Identification and Validation Targeted Protein Degradation

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Self Service DNA Encoded Library Screening

Resource Type: Webinar
Resource Topic: Biophysical Assays DNA-Encoded Library (DEL) Hit Finding Small Molecules Target Identification and Validation

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Resource Topics
× peptide, amino acid

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