Knowledge Library

XPRESS Portfolio: Off-the-Shelf Crystallography

XPRESS Portfolio Over 150 targets enabled for off-the-shelf crystallography Broad range of targets and classes Established protocols for protein production and crystallization Average turn-around time of 2 months

Resource Type: Brochure Latest Science
Resource Topic: Biophysical Assays Structural Biology

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Computer-Aided Drug Discovery Services

Resource Type: Brochure
Resource Topic: DRUG DISCOVERY AND INNOVATION Hit Finding in silico services

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Ready-to-Go Biophysical Assays

We offer a comprehensive platform of biophysical screening assays to measure protein binding, thermodynamics, stoichiometry, protein quality, and kinetics to accelerate your drug discovery programs.

Resource Type: Brochure
Resource Topic: Biophysical Assays Hit-to-Lead Lead Optimization Structural Biology

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Cutting-Edge Crystallography Services

Discover our comprehensive structure generation platform for challenging targets, with our high resolution and high throughput crystallization services to support hit finding through to lead optimization.

Resource Type: Brochure
Resource Topic: Hit Finding Hit-to-Lead Lead Optimization Structural Biology

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Crystal-Grade Protein Production

With a focus on quality and stability, gain access to our established systems, strategies, and advanced co-expression vectors to address even the most significant challenges of recombinant protein production.

Resource Type: Brochure
Resource Topic: Biophysical Assays Mass Spectrometry-based Assays Structural Biology Target Identification and Validation

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WuXi Biology Fact Sheet

Expertise in all major disease areas and all major target classes, enabling discovery for all therapeutic modalities World class antiviral platform with an unequalled service capability and capacity in HBV and other viral diseases A global leader in DNA Encoded Library (DEL) screening, with innovative business models CAP-certified pathology and FACS capabilities supporting clinical biomarker …Read More >

Resource Type: Brochure Latest Science
Resource Topic: DRUG DISCOVERY AND INNOVATION TECHNOLOGY PLATFORMS THERAPEUTIC AREAS

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Targeted Protein Degradation

WuXi AppTec utilizes state-of-the-art techniques to support drug discovery teams focused on targeted protein degradation. Our services include a broad range of ligand-finding methods, such as DEL, fragment screening, ASMS, and virtual screening. We provide custom linker design and complex synthesis for new linkers and E3 ligase ligands. To support lead optimization efforts, our platform …Read More >

Resource Type: Brochure Latest Science
Resource Topic: Biochemical Assays Biophysical Assays Cell-based Assays Mass Spectrometry-based Assays Oncology Small Molecules Structural Biology Targeted Protein Degradation

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WuXi AppTec in vitro Neuroscience Services

Neurological disorders, such as neurodegenerative diseases, epilepsy, chronic pain, psychiatric disorders, are one of today’s largest unmet medical needs. However, due to poor disease and target understanding, Neuroscience drug discovery can be very challenging. An open access research platform with dedicated neuroscience specialists and integrated services will be an ideal partner throughout your drug discovery …Read More >

Resource Type: Brochure
Resource Topic: Antibodies Biochemical Assays Biomarkers Cell-based Assays Cells and Protein Science Central Nervous System & Pain Hit Finding Hit-to-Lead in vitro biology Lead Optimization Phenotypic Assays Rare Diseases Safety and Early Toxicity Small Molecules Target Identification and Validation

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WuXi AppTec Oligonucleotide Biology Platform

We offer a wide range of oligonucleotide services, including: Sequence design Knockdown effect in cell lines and primary cells Splicing analysis Functional assays and assessment of off-target effects Transgenic, HDI and AAV mouse models GalNAc-ASGPR delivery system and customized assays for other delivery systems Stability and protein-protein binding assays Delivery/RISC PK in mouse, rat, and …Read More >

Resource Type: Brochure
Resource Topic: Biochemical Assays Candidate Selection Cell-based Assays Discovery Chemistry Gene Therapies Hit-to-Lead in vivo Pharmacology Lead Optimization Liver Diseases Oligonucleotides Rare Diseases Safety and Early Toxicity Target-Specific Assays

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Resource Topics
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