Knowledge Library

Protein Science Platform

Benefiting from 15 years of expertise in protein production, the protein science platform within WuXi Biology has successfully served hundreds of global clients. Our protein science specialists are at the forefront of drug discovery efforts, offering a wide range of services including protein production, isotope labeling, and customized conjugation across all major target classes. We …Read More >

Resource Type: Brochure, Case Study
Resource Topic: Cells and Protein Science

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Oligonucleotide Services

Choose excellence, choose WuXi Biology- your reliable partner in oligonucleotide drug discovery. WuXi Biology provides an integrated service platform for support of the discovery of oligonucleotide drugs. Our services cover sequence and modification design of oligonucleotides, in vitro and in vivo biological and PK/PD evaluations, and assessment of oligonucleotide off-target effects. Our broad and deep …Read More >

Resource Type: Brochure
Resource Topic: Oligonucleotides

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mRNA Services Platform

Design and production of mRNA Design and optimization of mRNA sequences Utilizing the design and optimization techniques for mRNA sequences, UTR screening, and codon optimization Plasmid and DNA template productions for in vitro transcription Employment of a classical three-step purification method Implementation of mono-enzyme digestion and purification through chromatography Research scale mRNA production and characterization …Read More >

Resource Type: Brochure
Resource Topic: Oligonucleotides

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Infectious Disease Platform

Capacity Comprehensive virus, bacteria, fungi coverages Supporting drug and vaccine discovery from early research to clinical trials Capability 20+ various viruses Supporting discovery of antivirals and vaccines, including HBV, SARS-CoV, IFV, RSV, HCV, HIV, EV71, herpes, rabies, and other viruses 130+ different bacterial and fungal species Supporting discovery of antibacterial and antifungal therapeutics, including ESKAPE, …Read More >

Resource Type: Brochure
Resource Topic: Infectious Diseases

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Hepatobiliary Disease Platform

The hepatobiliary system (comprised of the liver, gallbladder, and bile ducts) plays an important role in digestion and in the biotransformation and disposition of endogenous molecules and drugs. Hepatobiliary diseases range from minor infection or scarring to serious conditions such as cancer. At this year’s EASL conference, WuXi AppTec showcased our comprehensive platform of hepatobiliary-related …Read More >

Resource Type: Brochure
Resource Topic: in vivo Pharmacology, Liver Diseases, NASH

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Antibody Discovery Platform

WuXi AppTec provides integrated and cost-effective services for: Polyclonal and monoclonal antibodies Anti-drug antibodies (ADA), host cell protein (HCP) antibodies, surrogate antibodies, diagnostic antibodies, therapeutic antibodies Antibody drug conjugate services, including site-specific conjugation Related antibody services, including peptide design and recombinant protein production

Resource Type: Brochure
Resource Topic: Antibodies, Antibody Drug Conjugate, Immunology, Oncology

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Cryo-EM

We offer established protocols for cryo-EM structure determination, with extensive experience in epitope mapping, formulation characterization, and structure-based drug discovery (SBDD). Our integrated services platform also includes: Biophysical and biochemical screening assays Crystal-grade protein production High-resolution X-ray crystallography

Resource Type: Brochure
Resource Topic: Cryo-EM, Structural Biology

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High Throughput Protein Production

We offer high-quality protein production with expertise across all major target classes. Our panel of services includes an automated multistep purification platform for fast parallelized production of high quality proteins, and QC/functionality testing via nanoDSF and MST techniques.

Resource Type: Brochure
Resource Topic: Structural Biology

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One Stop Target-to-Hit Platform: STATs

STAT proteins are key mediators of cellular immunity, proliferation, apoptosis, and differentiation.  STATs are known to play a role in the pathogenesis of many different diseases (including cancer) and the development of drugs directly or indirectly targeting STAT signaling has become a major focus for discovery teams.  WuXi AppTec offers a comprehensive platform of biophysical …Read More >

Resource Type: Brochure
Resource Topic: Biochemical Assays, Biophysical Assays, Immunology, Oncology, Structural Biology

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Resource Topics
× peptide, amino acid

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