Oncology Archives - Page 14 of 20

TEAD Proteins Associate With DNA Repair Proteins to Facilitate Cellular Recovery

WuXi AppTec scientists recently contributed to a research study which utilized an affinity purification mass spectrometry approach to identify nuclear...

Enzalutamide-resistant LNCaP ARF877L Mutation KI model

We have established an enzalutamide-resistant (LNCaP AR-F877L mutation) KI prostate cancer model to support the development of next-generation therapeutics. An...

Cancer Pharmacology Services

Offering a wide range of targeted oncology services and translational models. Our comprehensive platform includes: in vitro biochemical, biophysical, and...

Tumor Cell Panel | Screening Services

Comprehensive cell line screening assays integrated with downstream pharmacological services Cell panel of 600+ human cancer cell lines for single...

Clinical Biomarkers

Multidisciplinary testing platforms that enable support to detect, develop, and validate biomarkers of cancer. End-to-end services in pathology, flow cytometry,...

Rare Genetic Disease Platform

Oncology & Immunology Services From the generation and characterization of genetically engineered animal models (GEAMs) to colony management and pre-clinical...

DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2–p53 Inhibitor

Macrocyclic peptides are an emerging molecular class for targeting intracellular protein–protein interactions (PPIs) and for providing an oral modality for...

Orthotopic and Metastasis Syngeneic Models

Our comprehensive panel of orthotopic and metastasis syngeneic models includes: 17 orthotopic/disseminated models covering 10 cancer types; Organ-based orthotopic models...