Knowledge Library

How Does It Work? | Peptibodies

#Research has explored the ways to extend the half-life of peptide drugs. One innovative way to achieve this is by fusing #therapeutic peptides to the Fc region of an antibody to create what is known as a peptibody. When the peptibody is naturally taken up by cells it binds to an Fc (antibody) receptor within …Read More >

Resource Type: Video
Resource Topic: Antibodies, Cells and Protein Science, Oncology, Target-Specific Assays

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How Does It Work? | Targeted Protein Degrader

As part of our dedication to providing an #openaccess platform, so our entire ecosystem can come together to share #science & #collaborate to better the lives of all #patientsfirst. We’ve created MoA animations in our new series exploring biotech topics on a molecular level. First up, we explain the intricacies of how targeted protein degradation …Read More >

Resource Type: Video
Resource Topic: Biochemical Assays, Biophysical Assays, Cell-based Assays, Oncology, Target Identification and Validation, Targeted Protein Degradation

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How Does It Work? | RNAi

As part of our dedication to providing an #openaccess platform, so our entire ecosystem can come together to share #science & #collaborate to better the lives of all #patientsfirst. We’ve created MoA animations in our new series exploring biotech topics on a molecular level. Protein malfunctions cause many diseases, but a new approach is emerging …Read More >

Resource Type: Video
Resource Topic: Autoimmune and Inflammatory Diseases, Cardiovascular & Metabolic Diseases, Central Nervous System & Pain, DRUG DISCOVERY AND INNOVATION, Gene Therapies, Liver Diseases, Metabolic Diseases, Oligonucleotides, Oncology, Ophthalmology, Rare Diseases, Target Identification and Validation

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Quality Control for DNA-Encoded One-Bead-One-Compound (OBOC) Libraries

Resource Type: Presentation, Video
Resource Topic: Biochemical Assays, Biophysical Assays, Chemical Biology and Proteomics, DNA-Encoded Library (DEL), Hit Finding, in vitro biology, Phenotypic Assays, Screening Libraries, Small Molecules, Target Identification and Validation

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Discovery of RNA Targeting Small Molecule Using DNA-Encoded Library Technology

Resource Type: Presentation, Video
Resource Topic: DNA-Encoded Library (DEL), Hit Finding

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Integrating Practical Machine Learning and Quantum Mechanics Tools to Synthesis in Medicinal Chemistry

Resource Type: Presentation, Video
Resource Topic: Chemical Biology and Proteomics, Discovery Chemistry, in silico services, Quantum Mechanics, Small Molecules

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DNA-Encoded Libraries in Drug Discovery – Advances in Screening and Chemistry

Resource Type: Presentation, Video
Resource Topic: DNA-Encoded Library (DEL), Hit Finding, Screening Libraries, Small Molecules, Target Identification and Validation

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Enable Pharma and Biotech Innovation through Open-Access Platform

Resource Type: Presentation, Video
Resource Topic: Biochemical Assays, Biophysical Assays, Cell-based Assays, Target Identification and Validation, Targeted Protein Degradation

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Fragment Screening and Biophysical Hit Validation at WuXi AppTec’s HitS

Resource Type: Presentation, Video
Resource Topic: Biochemical Assays, Biophysical Assays, Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Lead Optimization, Small Molecules, Structural Biology

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Resource Topics
× peptide, amino acid

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