One Stop Target-to-Hit Platform: Werner Syndrome Helicase (WRN)

Werner syndrome helicase (WRN) is a key drug target for cancers with microsatellite instability.  To support the discovery of potent and selective WRN inhibitors, WuXi AppTec offers a comprehensive platform of biophysical and biochemical assays to support hit finding and lead optimization efforts targeting WRN.  Our panel of services also include high-quality WRN protein production and established X-ray crystallography protocols.



Werner Syndrome Helicase Platform

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