One Stop Target-to-Hit Platform: Cyclin-dependent kinase 2 (CDK2)

Cyclin-dependent kinase 2 (CDK2) and its respective cyclin E1 and cyclin A2 complexes are essential to driving abnormal growth processes in cancer cells, making these proteins important targets for cancer treatment.  To support the discovery of novel CDK2 inhibitors, WuXi AppTec offers a comprehensive platform of biophysical and biochemical assays to accelerate hit finding and lead optimization efforts targeting CDK2.  Our panel of services also includes high-quality CDK2 and CDK2-complex protein production and established X-ray crystallography protocols.



CDK2-cyclin E1_cyclin A2_platform_v2a

Download

← Return to Resources

Related Content

STAT proteins are key mediators of cellular immunity, proliferation, apoptosis, and differentiation.  STATs are known to play a role in...

VIEW RESOURCE

At the Covalent Drug Discovery 2023 Summit and Fragments 2024 Conference, we presented a case study on Bruton’s tyrosine kinase (BTK)...

VIEW RESOURCE
← View all Biochemical Assays Resources
× peptide, amino acid

Contact An Expert Today!