Knowledge Library
WuXi AppTec Discovery Services
Delivering comprehensive end-to-end solutions for creating, identifying, and supporting preclinical candidates, from discovery to development, with our integrated chemistry and biology research platforms.
Resource Type: Brochure
Resource Topic: Antibodies, Antibody Drug Conjugate, Autoimmune and Inflammatory Diseases, Biochemical Assays, Biomarkers, Biophysical Assays, Candidate Selection, CAR-T Cell, Cardiovascular & Metabolic Diseases, Cell Therapies, Cell-based Assays, Cells and Protein Science, Central Nervous System & Pain, Chemical Biology and Proteomics, Dermatology, Discovery Chemistry, DNA-Encoded Library (DEL), DRUG DISCOVERY AND INNOVATION, Fragment-Based Drug Discovery, Gene Therapies, High-throughput screening (HTS), Hit Finding, Hit-to-Lead, Immunology, in silico services, in vitro biology, in vivo Pharmacology, in vivo Toxicology, Infectious Diseases, Lead Optimization, Liver Diseases, Mass Spectrometry-based Assays, Metabolic Diseases, NASH, Oligonucleotides, Oncology, Oncolytic Viruses, Ophthalmology, Phenotypic Assays, Quantum Mechanics, Rare Diseases, Respiratory Diseases, Safety and Early Toxicity, Screening Libraries, Screening Services, Small Molecules, Structural Biology, Target Identification and Validation, Target-Specific Assays, Targeted Protein Degradation, TECHNOLOGY PLATFORMS, THERAPEUTIC AREAS, THERAPEUTIC MODALITIES, Tumor Models
NASH Animal Models and their Clinical Relevance – Quantitative Histopathology of Hepatic Fibrosis
Resource Type: Webinar
Resource Topic: Biomarkers, Lead Optimization, Liver Diseases, Metabolic Diseases, NASH
Novel Strategies to Accelerate Discovery of Translatable Therapeutic Targets
Resource Type: Webinar
Resource Topic: Biomarkers, Hit Finding, Hit-to-Lead, in silico services, Liver Diseases, Oncology, Target Identification and Validation
Quantitative Histopathology of Fibrosis in an Animal Model of NASH
The hepatic fibrosis has been the most challenging aspect in the animal models for nonalcoholic steatohepatitis (NASH). Although it could induced by nutritional (high-fat died with high cholesterol, methionine and choline deficient diet, etc), chemical (carbon tetrachloride, thioacetamide, α-naphthylisothiocyanate etc.), and surgical (bile duct ligation) means, the clinical relevance of the resulting fibrosis remains an …Read More >
Resource Type: Article, Blog
Resource Topic: Biomarkers, Candidate Selection, Liver Diseases, Metabolic Diseases, NASH
