Knowledge Library

WuXi AppTec in vitro Neuroscience Services

Neurological disorders, such as neurodegenerative diseases, epilepsy, chronic pain, psychiatric disorders, are one of today’s largest unmet medical needs. However, due to poor disease and target understanding, Neuroscience drug discovery can be very challenging. An open access research platform with dedicated neuroscience specialists and integrated services will be an ideal partner throughout your drug discovery …Read More >
Resource Type: Brochure
Resource Topic: Antibodies, Biochemical Assays, Biomarkers, Cell-based Assays, Cells and Protein Science, Central Nervous System & Pain, Hit Finding, Hit-to-Lead, in vitro biology, Lead Optimization, Phenotypic Assays, Rare Diseases, Safety and Early Toxicity, Small Molecules, Target Identification and Validation

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OncoWuXi Newsletter November 2022
Resource Type: Newsletter
Resource Topic: Antibodies, Antibody Drug Conjugate, Autoimmune and Inflammatory Diseases, Biomarkers, Cell-based Assays, Cells and Protein Science, Hit-to-Lead, Lead Optimization, Oncology

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How Does It Work? | Protein Based Vaccines

When a new pathogen invades, it’s a race against time for your immune system to stop it from multiplying out of control. This week, we explore Protein Based Vaccines as part of our “How Does It Work?” series. Fortunately, #vaccines give your immune system a head start against dangerous pathogens. A protein-based vaccine, like this …Read More >
Resource Type: Video
Resource Topic: Cells and Protein Science, Infectious Diseases, Target Identification and Validation

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How Does It Work? | Peptibodies

#Research has explored the ways to extend the half-life of peptide drugs. One innovative way to achieve this is by fusing #therapeutic peptides to the Fc region of an antibody to create what is known as a peptibody. When the peptibody is naturally taken up by cells it binds to an Fc (antibody) receptor within …Read More >
Resource Type: Video
Resource Topic: Antibodies, Cells and Protein Science, Oncology, Target-Specific Assays

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PD-1 Blockade Protein in 4th Generation Armored CAR-T Cells Enhances Cytotoxicity Effect with in vitro Re-challenge System

Chimeric antigen receptor (CAR)-T cells are genetically engineered T cells that express a surface receptor to recognize tumor-associated antigens (TAA). CAR-T cell therapy have demonstrated remarkable success with hematological malignancies. However, limited headway has been made towards solid tumor, due to various challenges, including recognition of tumor-specific antigen trafficking and penetration, localization and survival within …Read More >
Resource Type: Latest Science, Poster
Resource Topic: Antibodies, Biomarkers, CAR-T Cell, Cell Therapies, Cell-based Assays, Cells and Protein Science, Oncology, Target Identification and Validation

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WuXi AppTec Discovery Services

Delivering comprehensive end-to-end solutions for creating, identifying, and supporting preclinical candidates, from discovery to development, with our integrated chemistry and biology research platforms.  
Resource Type: Brochure
Resource Topic: Antibodies, Antibody Drug Conjugate, Autoimmune and Inflammatory Diseases, Biochemical Assays, Biomarkers, Biophysical Assays, Candidate Selection, CAR-T Cell, Cardiovascular & Metabolic Diseases, Cell Therapies, Cell-based Assays, Cells and Protein Science, Central Nervous System & Pain, Chemical Biology and Proteomics, Dermatology, Discovery Chemistry, DNA-Encoded Library (DEL), DRUG DISCOVERY AND INNOVATION, Fragment-Based Drug Discovery, Gene Therapies, High-throughput screening (HTS), Hit Finding, Hit-to-Lead, Immunology, in silico services, in vitro biology, in vivo Pharmacology, in vivo Toxicology, Infectious Diseases, Lead Optimization, Liver Diseases, Mass Spectrometry-based Assays, Metabolic Diseases, NASH, Oligonucleotides, Oncology, Oncolytic Viruses, Ophthalmology, Phenotypic Assays, Quantum Mechanics, Rare Diseases, Respiratory Diseases, Safety and Early Toxicity, Screening Libraries, Screening Services, Small Molecules, Structural Biology, Target Identification and Validation, Target-Specific Assays, Targeted Protein Degradation, TECHNOLOGY PLATFORMS, THERAPEUTIC AREAS, THERAPEUTIC MODALITIES, Tumor Models

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Structure determination: comparison of methods

WuXi AppTec offers comprehensive structural generation solutions for today´s challenging targets. Our experts provide insights and data to support hit finding through to lead optimization.
Resource Type: Brochure, Infographic
Resource Topic: Biophysical Assays, Cells and Protein Science, Hit Finding, Hit-to-Lead, Lead Optimization, Structural Biology, Target Identification and Validation

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One-Stop Target-to-Hit Solutions

WuXi AppTec  | Target-to-Hit Solutions Protein Production  | All Target Classes and Challenging Proteins Biophysical & Biochemical Platforms |  Ready-To-Go Assay for Broad Range of Drug Targets Structural Biology Platforms Covalent and non-covalent fragment libraries & Screening
Resource Type: Brochure
Resource Topic: Biochemical Assays, Biophysical Assays, Cells and Protein Science, Chemical Biology and Proteomics, Discovery Chemistry, DNA-Encoded Library (DEL), Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Lead Optimization, Mass Spectrometry-based Assays, Screening Libraries, Small Molecules, Structural Biology, Target Identification and Validation

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Immuno-Oncology Platform to Enable Discovery from Target to Drug
Resource Type: Presentation, Video
Resource Topic: Biomarkers, Cell-based Assays, Cells and Protein Science, DRUG DISCOVERY AND INNOVATION, Hit Finding, Hit-to-Lead, Lead Optimization, Oncology, Screening Libraries, Target Identification and Validation, Tumor Models

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Resource Topics
× peptide, amino acid

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