Knowledge Library
WuXi Biology GPCR Cell Lines and Assays
G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors in eukaryotes and play a pivotal role in signaling pathways, making these transmembrane proteins an important drug target class. In recent years, GPCR drug discovery has moved from random ligand screening towards structure-based drug design. WuXi Biology has developed an integrated GPCR …Read More >
Resource Type: Brochure
Resource Topic: Biochemical Assays, Cell-based Assays, Hit-to-Lead, Lead Optimization, Metabolic Diseases, Oncology, Small Molecules, Target Identification and Validation, Target-Specific Assays
One-Stop Target-to-Hit Solutions
WuXi AppTec | Target-to-Hit Solutions Protein Production | All Target Classes and Challenging Proteins Biophysical & Biochemical Platforms | Ready-To-Go Assay for Broad Range of Drug Targets Structural Biology Platforms Covalent and non-covalent fragment libraries & Screening
Resource Type: Brochure
Resource Topic: Biochemical Assays, Biophysical Assays, Cells and Protein Science, Chemical Biology and Proteomics, Discovery Chemistry, DNA-Encoded Library (DEL), Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Lead Optimization, Mass Spectrometry-based Assays, Screening Libraries, Small Molecules, Structural Biology, Target Identification and Validation
Target to Hit Finding: New Methods in Fragment-Based Drug Discovery
Resource Type: Webinar
Resource Topic: Biochemical Assays, Biophysical Assays, Fragment-Based Drug Discovery, Hit Finding, Screening Libraries, Small Molecules, Target Identification and Validation, Target-Specific Assays
Enable Pharma and Biotech Innovation through Open-Access Platform
Resource Type: Presentation, Video
Resource Topic: Biochemical Assays, Biophysical Assays, Cell-based Assays, Target Identification and Validation, Targeted Protein Degradation
Fragment Screening and Biophysical Hit Validation at WuXi AppTec’s HitS
Resource Type: Presentation, Video
Resource Topic: Biochemical Assays, Biophysical Assays, Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Lead Optimization, Small Molecules, Structural Biology
Enabling Technologies for Targeted Protein Degradation Webinar
Resource Type: Webinar
Resource Topic: Biochemical Assays, Biophysical Assays, Cell-based Assays, Discovery Chemistry, Small Molecules, Target Identification and Validation, Target-Specific Assays, Targeted Protein Degradation
Enabling Technologies For Bifunctional Molecule Discovery And Characterization
Resource Type: Webinar
Resource Topic: Biochemical Assays, Biophysical Assays, Cell-based Assays, Discovery Chemistry, Small Molecules, Structural Biology, Target Identification and Validation, Target-Specific Assays, Targeted Protein Degradation
Cancer Immunotherapy and the Application of In Vitro Immunoassays in Drug Development
Resource Type: Webinar
Resource Topic: Antibodies, Autoimmune and Inflammatory Diseases, Biochemical Assays, Cell-based Assays, Hit-to-Lead, Immunology, Lead Optimization, Oncology, Phenotypic Assays, Small Molecules, Target Identification and Validation, Target-Specific Assays
Optimizing Drug Discovery Pipelines with Biophysical Methods
Resource Type: Webinar
Resource Topic: Antibodies, Biochemical Assays, Biomarkers, Biophysical Assays, Cell-based Assays, DNA-Encoded Library (DEL), Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Mass Spectrometry-based Assays, Oncology, Phenotypic Assays, Screening Libraries, Small Molecules, Structural Biology, Target Identification and Validation, Target-Specific Assays, Targeted Protein Degradation