DNA-encoded chemical libraries
https://www.nature.com/articles/s43586-021-00084-5 Abstract DNA-encoded chemical library (DECL) technology is used by the pharmaceutical industry to discover small molecules capable of modulating...
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Introduction into Fragment Based Drug Discovery
Fragment-based drug discovery (FBDD) is a method used for finding hit compounds as one strategy of hit identification in the...
Continue Reading Drugging the Undruggable: Leveraging the Right Screening Methods for Challenging Targets
Challenging targets, such as membrane proteins or protein-protein interactions were considered undruggable in the past. However, today a variety of...
Continue Reading WuXi AppTec in vitro Neuroscience Services
Neurological disorders, such as neurodegenerative diseases, epilepsy, chronic pain, psychiatric disorders, are one of today’s largest unmet medical needs. However,...
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How Does It Work? | Adenovirus Vaccines
This week, we delve into Adenovirus Vaccines as part of our “How Does It Work?” 3D MoA animation series examining...
Continue Reading How Does It Work? | mRNA Vaccines
If you’ve ever read about mRNA vaccines and wondered, “How Does It Work?” This week’s installment of our video series...
Continue Reading How Does It Work? | Peptide-Oligonucleotide Conjugates
This week’s episode of our “How Does It Work?” series features Peptide-Oligonucleotide Conjugates. Peptide-oligonucleotide conjugates are made up of peptide...
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