Knowledge Library
DNA-encoded libraries for academic – DELopen Handbook
DNA-encoded libraries for academic | Open Access to DEL Self-service platform for academia to utilize the full potential of DEL technology DELopen provides free access to DNA-encoded libraries (DEL) for academic users and encourages an open, community-based approach to data sharing.
DEL Screening – DELight Handbook
DEL Screening | WuXi AppTec DELight Kit Faster and Lighter Drug Discovery DELight kit containing 58 libraries and 10.8 billion compounds, buffers and a step-by-step online experimental manual. Drug developers perform affinity selection according to the manual and return the sample to WuXi AppTec upon completion.
Cell Line-Derived Xenograft (CDX) Tumor Models
A large collection of cell line-derived xenograft (CDX) tumor models 215 validated models, SOC data available World leading imaging based orthotopic/metastatic CDX platform 28 models covering 16 tumor types
WuXi Oncology and Immuno-Oncology Services
Integrated Oncology and Immuno-oncology Platform to Enable Translational Science from Drug Discovery to Clinical Biomarker Oncology Services CRISPR/Cas9 Gene Editing In Vitro Assay and HTS Tumor models Tumor Cell Panel and Screening Immunology and Immuno-oncology Platform Clinical Biomarker Immunology Services Ligand-receptor binding assays Cellular functional assays Assays for innate immunity pathways: macrophage, MDSC, NK, DC, …Read More >
Identification of Tofacitinib, Filgotinib and Ruxolitinib on experimental Sjögren’s syndrome model in mice
Sjögren’s syndrome, which affects hundreds of millions of people worldwide, is a chronic autoimmune disorder characterized by leukocytic infiltration into the exocrine glands, such as the salivary and lacrimal glands. However, the pathological mechanism remains to be elucidated, and novel treatments are urgently needed. Over the past decade, extensive progress has been made in the …Read More >