Knowledge Library
Bifunctional Molecules: A Diverse New Modality That Unlocks New Target Classes
Quantum Mechanics for Organic Chemists: An Experimentalist Approach
Magical Power of Quantum Mechanics EBook Would you like to predict organic reaction outcomes accurately? Design synthetic sequences with higher rate of success? Would you prefer to learn and rationalize organic chemistry in a data-driven manner? Quantum Mechanics (QM) tools for chemistry are evolving at a tremendously fast pace and have proven to be invaluable for …Read More >
Targeted Protein Degradation Platform
Integrated Services BIOLOGY & PHARMACOLOGY BINARY/TERNARY COMPLEX FORMATION Biochemical & Biophysical Assays Biochemical binding assay Cellular Assays TARGET UBIQUITINATION & DEGRADATION In vitro Assays-Target ubiquitination Target degradation assay PK/PD Animal Disease Model Evaluation CHEMISTRY Specific virtual library design Compound synthesis Conjugation and all type of custom syntheses from milligram to kilogram scale Purification and analytical …Read More >
One-stop DEL services from target to hit series – DELpro
WuXi AppTec provides a one-stop solution for DEL services from target to hit series. Our extended platform enables overall planning and management of protein production, DEL library production, affinity selection, data analysis, hit validation and structural biology for further optimization.
Open Access to DEL for data sharing – DELopen
DELopen platform is dedicated to the development and application of DEL technology in drug discovery. Free access to DEL, data sharing. DELopen encourages an open, community-based approach to data sharing and exploration of the capabilities of DEL technology. We envision that DELopen will help academia benefits from the efficiency of DEL and unlock the full …Read More >
DNA-encoded libraries for academic – DELopen Handbook
DNA-encoded libraries for academic | Open Access to DEL Self-service platform for academia to utilize the full potential of DEL technology DELopen provides free access to DNA-encoded libraries (DEL) for academic users and encourages an open, community-based approach to data sharing.
DEL Screening – DELight Handbook
DEL Screening | WuXi AppTec DELight Kit Faster and Lighter Drug Discovery DELight kit containing 58 libraries and 10.8 billion compounds, buffers and a step-by-step online experimental manual. Drug developers perform affinity selection according to the manual and return the sample to WuXi AppTec upon completion.
Cell Line-Derived Xenograft (CDX) Tumor Models
A large collection of cell line-derived xenograft (CDX) tumor models 215 validated models, SOC data available World leading imaging based orthotopic/metastatic CDX platform 28 models covering 16 tumor types
WuXi Oncology and Immuno-Oncology Services
Integrated Oncology and Immuno-oncology Platform to Enable Translational Science from Drug Discovery to Clinical Biomarker Oncology Services CRISPR/Cas9 Gene Editing In Vitro Assay and HTS Tumor models Tumor Cell Panel and Screening Immunology and Immuno-oncology Platform Clinical Biomarker Immunology Services Ligand-receptor binding assays Cellular functional assays Assays for innate immunity pathways: macrophage, MDSC, NK, DC, …Read More >
