Knowledge Library

WuXi AppTec in vitro Neuroscience Services

Neurological disorders, such as neurodegenerative diseases, epilepsy, chronic pain, psychiatric disorders, are one of today’s largest unmet medical needs. However, due to poor disease and target understanding, Neuroscience drug discovery can be very challenging. An open access research platform with dedicated neuroscience specialists and integrated services will be an ideal partner throughout your drug discovery …Read More >

Resource Type: Brochure
Resource Topic: Antibodies Biochemical Assays Biomarkers Cell-based Assays Cells and Protein Science Central Nervous System & Pain Hit Finding Hit-to-Lead in vitro biology Lead Optimization Phenotypic Assays Rare Diseases Safety and Early Toxicity Small Molecules Target Identification and Validation

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OncoWuXi Newsletter November 2022

Resource Type: Latest Science Newsletter
Resource Topic: Antibody Drug Conjugate Autoimmune and Inflammatory Diseases Cell-based Assays Cells and Protein Science Oncology

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How Does It Work? | CRISPR Mechanism

The CRISPR Cas9 System was first discovered as part of the bacterial adaptive immune response against viruses, but in recent years it’s revolutionized our techniques for genome editing. The Cas9 complex is formed of two components. A protein called Cas9 that can cut double stranded DNA, and a guide RNA, that binds to a specific …Read More >

Resource Type: Video
Resource Topic: CRISPR/Cas9 Gene Manipulation Gene Therapies in vivo Pharmacology Oncology Target Identification and Validation

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How Does It Work? | Protein Based Vaccines

When a new pathogen invades, it’s a race against time for your immune system to stop it from multiplying out of control. This week, we explore Protein Based Vaccines as part of our “How Does It Work?” series. Fortunately, #vaccines give your immune system a head start against dangerous pathogens. A protein-based vaccine, like this …Read More >

Resource Type: Video
Resource Topic: Cells and Protein Science Infectious Diseases Target Identification and Validation

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How Does It Work? | Adenovirus Vaccines

This week, we delve into Adenovirus Vaccines as part of our “How Does It Work?” 3D MoA animation series examining biotech topics on a molecular level. In 2020, the World Health Organization declared the Covid-19 outbreak a pandemic, but not all viruses are bad news. Adenoviruses are a family of viruses that can be used …Read More >

Resource Type: Video
Resource Topic: DRUG DISCOVERY AND INNOVATION Gene Therapies Infectious Diseases Target Identification and Validation

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How Does It Work? | mRNA Vaccines

If you’ve ever read about mRNA vaccines and wondered, “How Does It Work?” This week’s installment of our video series was made with you in mind. To understand how mRNA vaccines work, let’s take a close look at the immune system. Your immune system can recognize that the structures on bacteria or viruses are different …Read More >

Resource Type: Video
Resource Topic: Infectious Diseases Oligonucleotides Target Identification and Validation

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How Does It Work? | Peptide-Oligonucleotide Conjugates

This week’s episode of our “How Does It Work?” series features Peptide-Oligonucleotide Conjugates. Peptide-oligonucleotide conjugates are made up of peptide and oligonucleotide components. These cutting-edge molecules have many applications in biomedicine. The oligonucleotide component can interact with mRNA to alter gene expression within diseased cells but oligonucleotides are easily degraded in the body and have …Read More >

Resource Type: Video
Resource Topic: Autoimmune and Inflammatory Diseases Biochemical Assays Cell-based Assays Central Nervous System & Pain Gene Manipulation Oligonucleotides Oncology Target Identification and Validation

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How Does It Work? | Aptamers

Nucleic acids have long been regarded as biological compounds for storing and transferring information. However, their functionalities are far more diverse than this – ranging from gene regulation to enzymatic catalysis. One type of unconventional nucleic acid is the aptamer. Aptamers are short, single stranded nucleic acids that fold into highly specific structures. They bind …Read More >

Resource Type: Video
Resource Topic: Biomarkers Oligonucleotides Oncology Target Identification and Validation

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How Does It Work? | Individualized Oligonucleotide Therapies

In this week’s episode of our “How Does It Work?” video series, we explore Individualized Oligonucleotide Therapies. Around 6 billion letters form the genetic code that makes each person’s biology unique. Genomic sequencing allows us to read this code to find defects that cause disease, enabling us to tailor therapies for individual patients. This was …Read More >

Resource Type: Video
Resource Topic: Autoimmune and Inflammatory Diseases Central Nervous System & Pain Gene Manipulation Oligonucleotides Oncology Target Identification and Validation

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