Knowledge Library

Optimizing Drug Pipelines With Biophysical Methods

Download our whitepaper on how using biophysical techniques can enhance and streamline processes throughout the drug discovery and validation cycle. Discover fresh opportunities to characterize challenging drug targets, examine biophysical screening methods, and look toward what’s next for biophysical methods in drug discovery.

Resource Type: White Paper
Resource Topic: Biochemical Assays, Biophysical Assays, Discovery Chemistry, DNA-Encoded Library (DEL), Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Mass Spectrometry-based Assays, Screening Libraries, Small Molecules, Structural Biology, Target Identification and Validation, Target-Specific Assays

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Structure determination: comparison of methods

WuXi AppTec offers comprehensive structural generation solutions for today´s challenging targets. Our experts provide insights and data to support hit finding through to lead optimization.

Resource Type: Brochure, Infographic
Resource Topic: Biophysical Assays, Cells and Protein Science, Hit Finding, Hit-to-Lead, Lead Optimization, Structural Biology, Target Identification and Validation

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One-Stop Target-to-Hit Solutions

WuXi AppTec  | Target-to-Hit Solutions Protein Production  | All Target Classes and Challenging Proteins Biophysical & Biochemical Platforms |  Ready-To-Go Assay for Broad Range of Drug Targets Structural Biology Platforms Covalent and non-covalent fragment libraries & Screening

Resource Type: Brochure
Resource Topic: Biochemical Assays, Biophysical Assays, Cells and Protein Science, Chemical Biology and Proteomics, Discovery Chemistry, DNA-Encoded Library (DEL), Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Lead Optimization, Mass Spectrometry-based Assays, Screening Libraries, Small Molecules, Structural Biology, Target Identification and Validation

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Fragment Screening and Biophysical Hit Validation at WuXi AppTec’s HitS

Resource Type: Presentation, Video
Resource Topic: Biochemical Assays, Biophysical Assays, Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Lead Optimization, Small Molecules, Structural Biology

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New Platform from Target-to-Hit

Resource Type: Webinar
Resource Topic: Biophysical Assays, Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Mass Spectrometry-based Assays, Screening Libraries, Small Molecules, Structural Biology, Target Identification and Validation, Target-Specific Assays

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Enabling Technologies For Bifunctional Molecule Discovery And Characterization

Resource Type: Webinar
Resource Topic: Biochemical Assays, Biophysical Assays, Cell-based Assays, Discovery Chemistry, Small Molecules, Structural Biology, Target Identification and Validation, Target-Specific Assays, Targeted Protein Degradation

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Enabling Drug Discovery with Diverse Lead Generation Platforms

Resource Type: Webinar
Resource Topic: Discovery Chemistry, DNA-Encoded Library (DEL), Fragment-Based Drug Discovery, High-throughput screening (HTS), Hit Finding, Hit-to-Lead, in silico services, Lead Optimization, Mass Spectrometry-based Assays, Screening Libraries, Screening Services, Small Molecules, Structural Biology, Target Identification and Validation

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Optimizing Drug Discovery Pipelines with Biophysical Methods

Resource Type: Webinar
Resource Topic: Antibodies, Biochemical Assays, Biomarkers, Biophysical Assays, Cell-based Assays, DNA-Encoded Library (DEL), Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Mass Spectrometry-based Assays, Oncology, Phenotypic Assays, Screening Libraries, Small Molecules, Structural Biology, Target Identification and Validation, Target-Specific Assays, Targeted Protein Degradation

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Faster with high-speed fragment screening — Accelerate your drug discovery campaign

In the past, thousands of proteins were considered undruggable. The restricted number of chemical entities available and classical methods limited the exploration of this undevelopable area. Today, the combination of novel chemical modalities and advanced technical approaches has resulted in new clinical candidates from previously undruggable targets. To accelerate your drug discovery campaign, WuXi AppTec´s …Read More >

Resource Type: Article, Blog, Case Study
Resource Topic: Biochemical Assays, Biophysical Assays, Fragment-Based Drug Discovery, Hit Finding, Hit-to-Lead, Immunology, Lead Optimization, Small Molecules, Structural Biology

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Resource Topics
× peptide, amino acid

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