Resources Archive - WuXi Biology

In Vitro and In Vivo Efficacy of CAR-T Delivery

Targeted lipid nanoparticles (tLNPs) are advancing in vivo CAR-T therapies by facilitating the in situ generation of CAR-T effectors, offering...

In Vivo Evaluation of VEGF-Targeted Bispecific Antibodies

As PD-1/PD-L1 x VEGF-targeted bispecific antibodies gain momentum in oncology, selecting the right preclinical models is becoming increasingly important. These...

Drug-Resistant KRAS G12D Lung Cancer Models

KRAS G12D inhibitors continue to advance, but treatment resistance remains an important challenge. Understanding how that resistance develops is critical...

In Vivo CAR-T Preclinical Evaluation Platform

CAR-T therapies have transformed the treatment of hematologic malignancies, yet complex manufacturing, long production timelines, and high costs continue to...

A Novel Preclinical Mouse Model of Neutrophilic Asthma

Neutrophilic asthma remains one of the most challenging forms of asthma to study, with limited preclinical models available to support...

Advancing Conjugated Therapeutics: From ADC Innovation to Integrated Bioanalysis Strategies

Conjugated therapeutics, including antibody-drug conjugates (ADCs) and antibody-oligonucleotide conjugates (AOCs), are reshaping the future of targeted therapies and driving new...

A Novel Murine Model of MetALD for Therapeutic Drug Evaluation

Metabolic dysfunction-associated alcohol-related liver disease (MetALD) presents unique challenges for preclinical drug development, requiring models that capture the combined effects...

HPV18 Tumor Models for Cancer Vaccines and Immunotherapy

OncoWuXi Express will continue to keep you informed of updates to our online pharmacology model database (OncoWuXi Database) and our...

Semaglutide in Substance Use Disorders: Addiction Models

Substance Addiction Models and Pharmacodynamic Evaluation of Semaglutide in the Treatment of Substance Use Disorders OncoWuXi Express will continue to...

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