Knowledge Library

WuXi Discovery Services Newsletter: February 2021

Resource Type: Newsletter
Resource Topic: DNA-Encoded Library (DEL) Gene Therapies Target Identification and Validation Targeted Protein Degradation

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One-Stop Target-to-Hit Solutions

WuXi AppTec  | Target-to-Hit Solutions Protein Production  | All Target Classes and Challenging Proteins Biophysical & Biochemical Platforms |  Ready-To-Go Assay for Broad Range of Drug Targets Structural Biology Platforms Covalent and non-covalent fragment libraries & Screening

Resource Type: Brochure
Resource Topic: Biochemical Assays Biophysical Assays Cells and Protein Science Chemical Biology and Proteomics Discovery Chemistry DNA-Encoded Library (DEL) Fragment-Based Drug Discovery Hit Finding Hit-to-Lead Lead Optimization Mass Spectrometry-based Assays Screening Libraries Small Molecules Structural Biology Target Identification and Validation

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DELpro: A New Method of Hit Discovery

DNA-Encoded Library (DEL) technology involves a novel affinity selection process that integrates chemistry, biology, bioinformatics and computational chemistry to facilitate a rapid drug discovery process, allowing access to more chemical space with lower cost. In contrast to high throughput screening, DEL requires a very small amount of target protein and minimum assay development. More importantly, …Read More >

Resource Type: Brochure
Resource Topic: Chemical Biology and Proteomics DNA-Encoded Library (DEL) Hit Finding Screening Libraries Small Molecules Target Identification and Validation Targeted Protein Degradation

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Self Service DNA Encoded Library Screening

Resource Type: Webinar
Resource Topic: Biophysical Assays DNA-Encoded Library (DEL) Hit Finding Small Molecules Target Identification and Validation

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DNA-Encoded Libraries in Drug Discovery – Advances in Screening and Chemistry

Resource Type: Presentation Video
Resource Topic: DNA-Encoded Library (DEL) Hit Finding Screening Libraries Small Molecules Target Identification and Validation

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Introduction to Self-Service DNA-Encoded libraries (DELs)

Resource Type: Webinar
Resource Topic: DNA-Encoded Library (DEL) Hit Finding Screening Libraries Small Molecules Target Identification and Validation

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Enabling Drug Discovery with Diverse Lead Generation Platforms

Resource Type: Webinar
Resource Topic: Discovery Chemistry DNA-Encoded Library (DEL) Fragment-Based Drug Discovery High-throughput screening (HTS) Hit Finding Hit-to-Lead in silico services Lead Optimization Mass Spectrometry-based Assays Screening Libraries Screening Services Small Molecules Structural Biology Target Identification and Validation

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Optimizing Drug Discovery Pipelines with Biophysical Methods

Resource Type: Webinar
Resource Topic: Antibodies Biochemical Assays Biomarkers Biophysical Assays Cell-based Assays DNA-Encoded Library (DEL) Fragment-Based Drug Discovery Hit Finding Hit-to-Lead Mass Spectrometry-based Assays Oncology Phenotypic Assays Screening Libraries Small Molecules Structural Biology Target Identification and Validation Target-Specific Assays Targeted Protein Degradation

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Discovery of RNA binding molecule using DNA-encoded library technology

Resource Type: Webinar
Resource Topic: Chemical Biology and Proteomics Discovery Chemistry DNA-Encoded Library (DEL) Hit Finding Screening Libraries Small Molecules Target Identification and Validation

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Resource Topics
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