New study by Promega and WuXi AppTec demonstrates novel chemical probes from DELs

As reported in Business Wire:

DNA-Encoded Libraries (DELs) and NanoBRET Target Engagement Assays Accelerate Drug Discovery:

“The authors demonstrate that DELs can benefit chemical biologists who require verification of live cell target engagement for their protein of interest. This is particularly beneficial for understudied protein classes that may not have existing chemical probes. Additionally, they note that the NanoBRET assays help drug discovery researchers accelerate their workflow by providing data used to identify the most promising leads.”

Read the Business Wire news coverage here

Read the Open Access Paper entitled “DELs enable the development of BRET probes for target engagement studies in cells” by clicking here