WuXi Biology offers an integrated package of preclinical cancer pharmacology services for targeted oncology and immuno-oncology.  Our platform includes in vitro cell-free and cell-based assays, a comprehensive panel of in vivo tumor models, and multidisciplinary ex vivo PD analysis services. We have pioneered the development of over 1,500 PDX models across 30 cancer types, encompassing both …Read More >

As part of our neurobiology services platform, WuXi AppTec offers a comprehensive panel of advanced technologies and validated disease models to help project teams overcome the challenges in predicting the efficacy and safety of their lead candidates. • 200+ neurological preclinical models: comprehensive capabilities in neuropharmacology • Full-spectrum neurological coverage: from neurodegenerative diseases and neuropsychiatric disorders …Read More >

In the last decade, targeted protein degradation (TPD) technology has become one of the most promising methods to remove specific disease-related proteins using cellular self-destruction mechanisms. WuXi AppTec has built a robust TPD discovery platform, allowing for in-depth biological and biophysical characterization of monovalent (molecular glue) and bivalent (PROTAC®) molecules through the use of target …Read More >

WuXi AppTec offers a comprehensive platform of in silico drug discovery services to accelerate the process of hit finding and hit-to-lead optimization.  We provide access to virtual chemical spaces built from our library of novel drug-like scaffolds, to support virtual screening and structure-based virtual screening (SBVS). Advances in ML-empowered virtual screening allows project teams to …Read More >

Benefiting from 15 years of expertise in protein production, the Protein Science platform in WuXi Biology has successfully served hundreds of global clients. Our protein science specialists at the Munich and Suzhou sites are at the forefront of international drug discovery efforts, offering a wide range of services, including protein production and various techniques of …Read More >

Choose excellence, choose WuXi Biology- your reliable partner in oligonucleotide drug discovery. WuXi Biology provides an integrated service platform for support of the discovery of oligonucleotide drugs. Our services cover sequence and modification design of oligonucleotides, in vitro and in vivo biological and PK/PD evaluations, and assessment of oligonucleotide off-target effects. Our broad and deep …Read More >

Design and production of mRNA Design and optimization of mRNA sequences Utilizing the design and optimization techniques for mRNA sequences, UTR screening, and codon optimization Plasmid and DNA template productions for in vitro transcription Employment of a classical three-step purification method Implementation of mono-enzyme digestion and purification through chromatography Research scale mRNA production and characterization …Read More >

Capacity Comprehensive virus, bacteria, fungi coverages Supporting drug and vaccine discovery from early research to clinical trials Capability 20+ various viruses Supporting discovery of antivirals and vaccines, including HBV, SARS-CoV, IFV, RSV, HCV, HIV, EV71, herpes, rabies, and other viruses 130+ different bacterial and fungal species Supporting discovery of antibacterial and antifungal therapeutics, including ESKAPE, …Read More >

The hepatobiliary system (comprised of the liver, gallbladder, and bile ducts) plays an important role in digestion and in the biotransformation and disposition of endogenous molecules and drugs. Hepatobiliary diseases range from minor infection or scarring to serious conditions such as cancer. At this year’s EASL conference, WuXi AppTec showcased our comprehensive platform of hepatobiliary-related …Read More >