Mouse hind limb tumor metastatic model to evaluate prophylaxis and treatment
We have established and optimized a robust tumor bone metastasis mouse model, which recapitulates the tumor metastasis progression from circulation...
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Evaluating cancer therapies combining radiotherapy with immunotherapy or inhibitors of the DNA damage response
Ionizing radiation has largely been recognized as a local targeted therapy by a variety of mechanisms, including inducing direct DNA...
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Meeting Neurodegenerative Disease Head-On with Emerging Drug Discovery Strategies
Chronic neurodegenerative diseases encompass a variety of progressive conditions that affect neurons, including Huntington’s disease, Parkinson’s disease, Alzheimer’s disease, and...
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Evaluation of the efficacy of ADC in vitro and in vivo
Abstract Antibody drug conjugates (ADCs) are promising complexes with therapeutic potential that aimed to the treatment of solid tumor and...
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Structure determination: comparison of methods
WuXi AppTec offers comprehensive structural generation solutions for today´s challenging targets. Our experts provide insights and data to support hit...
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