Resources Archive - Page 21 of 48

Oligonucleotide Services

Choose excellence, choose WuXi Biology- your reliable partner in oligonucleotide drug discovery. WuXi Biology provides an integrated service platform for...

Infectious Disease Platform

Capacity Comprehensive virus, bacteria, fungi coverages Supporting drug and vaccine discovery from early research to clinical trials Capability 20+ various...

Hepatobiliary Disease Platform

The hepatobiliary system (comprised of the liver, gallbladder, and bile ducts) plays an important role in digestion and in the...

Expanded Role of PDX Models in Anticancer Drug Development

Expanded Role of PDX Models in Anticancer Drug Development Patient-derived xenograft (PDX) models are established by implanting surgically resected patient...

Preclinical Evaluation of JAK Inhibitors in an Atopic Dermatitis Model

Atopic dermatitis (AD) is a chronic, pruritic inflammatory skin condition that is characterized by recurrent eczematous lesions. Janus kinase (JAK)...

Rapamycin Ameliorates Renal Pathology in a Model of Passive Heymann Nephritis

Passive Heymann nephritis, induced by intravenous injection of anti-Fx1A in susceptible rat strains, is a complement-dependent model of glomerular disease...

Unveiling Mechanisms of CDK4-CDK6 Inhibitor Resistance in Breast Cancer Models

Cyclin-dependent kinases (CDKs) and their cyclin regulatory subunits form complexes that are essential for driving abnormal growth processes in cancer...

Targeted Protein Degradation of Mutant ER-alpha

Estrogen receptor α (ERα) is considered the main driver in more than 70% of all breast cancers, making this transcription...

siRNA Efficacy in a Xenograft Tumor Model

Protein kinase N3 (PKN3) is a serine/threonine kinase implicated in tumor progression across multiple cancer types. PKN3 mRNA is almost undetectable in normal adult...

Knowledge Library