Resources Archive - Page 2 of 46

mRNA Display: Unlocking Peptide Discovery

Introduction: In the realm of modern therapeutics, peptides have emerged as a powerful and versatile class of molecules, unlocking their...

Integrated Screening and Assay Capabilities Facilitate Peptide Drug Discovery

Peptide-based therapeutics have emerged as a significant class of drugs in the pharmaceutical landscape, offering numerous advantages, including high specificity,...

Combination Therapies in a Mouse MASH Model

Metabolic dysfunction-associated steatohepatitis (MASH), previously known as nonalcoholic steatohepatitis (NASH), is a serious liver disease. If left untreated, MASH can...

NHP Pain Animal Models

Introduction: OncoWuXi Express will continue to keep you informed about updates to our online pharmacology model database (OncoWuXi Database), as...

Strategies to Accelerate the Development of Antibody-Drug Conjugates

Antibody-drug conjugates (ADCs) hold great promise as cancer therapeutics, as they combine the precision of monoclonal antibodies with the potency...

Development of Rodent Models for Diabetic Neuropathy

Diabetic neuropathy, a common complication of diabetes, affects approximately 50% of diabetic patients and can lead to a range of...

STZ-Induced Diabetic Retinopathy Models

Diabetic retinopathy is a major contributor to vision loss and blindness in working-age adults with diabetes. Developing animal models that...

Overcoming PARP Inhibitor Resistance in an Olaparib-Induced Model

Poly (ADP-ribose) polymerase inhibitors (PARPi) have emerged as a promising therapeutic approach in the treatment of various cancers, particularly those...

Effects of Incretin-Based Therapies on Metabolic and Muscular Homeostasis

Advances in understanding how the body regulates metabolism, particularly the role of incretin hormones, have directly led to the development...

Knowledge Library