Knowledge Library

Immune Profiling Platform

We offer an extensive panel of cutting-edge immune profiling and biomarker discovery services to support: Target discovery and validation Drug efficacy assessment Mechanism of action and PD studies Identification of predictive biomarkers, to support patient stratification Check out our comprehensive platform of immunology services View our panel of biomarker and immune profiling services

Resource Type: Brochure
Resource Topic: Biomarkers Immunology Target Identification and Validation

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Tumor Cell Panel | Screening Services

Comprehensive cell line screening assays integrated with downstream pharmacological services Cell panel  of 600+ human cancer cell lines for single agent or combinatory drug screening, covering 30+ cancer types 100+ mouse cell lines, across 20+ cancer types 95 PDX-derived cell lines 320+ CDX models, ready for use 1,400+ PDX models, for primary tumor cell line …Read More >

Resource Type: Brochure
Resource Topic: Oncology Tumor Models

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Clinical Biomarkers

Multidisciplinary testing platforms that enable support to detect, develop, and validate biomarkers of cancer. End-to-end services in pathology, flow cytometry, and molecular biology techniques Rigorous quality management system, and well-established sample and data management procedures Multi-omics analysis utilizing multidisciplinary testing platforms CAP-accredited clinical biomarker lab has been established since 2015 View our comprehensive platform of …Read More >

Resource Type: Brochure
Resource Topic: Biomarkers Oncology

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Single-cell RNA Sequencing Services

Pilot Studies (selection of optimal time points and dosing) In vivo treatment Sample collection (from complex tissue to single cell isolation) Library preparation and sequencing Bioinformatics analysis View our cutting-edge immune profiling and biomarker platforms

Resource Type: Latest Science Presentation
Resource Topic: Biomarkers Cell-based Assays

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Research Chemistry Services

Delivering synthetic and medicinal chemistry solutions to global pharma and biotech customers for the discovery of hits, leads, and preclinical candidates. Check out our comprehensive panel of integrated, discovery chemistry services.

Resource Type: Brochure
Resource Topic: Discovery Chemistry Small Molecules

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Rare Genetic Disease Platform

Oncology & Immunology Services From the generation and characterization of genetically engineered animal models (GEAMs) to colony management and pre-clinical pharmacology research GEAM generation and characterization Full suite of in vitro testing assays Efficacy, toxicity, and PK/PD services Behavioral assessment platform Large in-house collection of GEAMs (KO/KI, mouse & rat) across multiple therapeutic areas, including: …Read More >

Resource Type: Brochure
Resource Topic: Immunology Oncology

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Immunology Assays

A comprehensive in vitro platform to accelerate cancer immunotherapy drug discovery: Binding & blocking assessment (via biophysical and biochemical assays, and flow cytometry) Immune cell activation (T cell, B cell, and NK cells) Immune cell suppression (MDSC and Treg suppressive assays) Immune T cell polarization and macrophage differentiation Antigen presentation/mixed lymphocyte reaction (including mouse allogenic …Read More >

Resource Type: Brochure
Resource Topic: Immunology

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Inflammatory Bowel Disease Models

We offer an extensive panel of inflammatory bowel disease models in mice and rats, including genetically modified, chemically induced, and adoptive transfer-related IBD models. Let our experts help you choose the best IBD animal models to advance your research programs. Learn more about our platform of inflammation models  

Resource Type: Latest Science Presentation
Resource Topic: Autoimmune and Inflammatory Diseases Hit-to-Lead in vivo Pharmacology Lead Optimization

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Regenerable Surface Plasmon Resonance (SPR) Surfaces for Reliable, Cost-Effective, and Wide-Ranging Applications

Traditional SPR-based drug discovery efforts in the small-molecule space have revolved around single-use chips for screening and hit-to-lead efforts. Inspired by recent technological advances, we have established simple regenerable protocols that can (1) accommodate target-proteins with common tags such as His- and Avi-, (2) reach sufficient surface density for small-molecule testing, and (3) maintain a …Read More >

Resource Type: Latest Science Poster
Resource Topic: Biophysical Assays

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Resource Topics
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