Resources Archive - Page 13 of 48

Metabolic Disease Services Platform

Metabolic diseases are considered to arise from multiple factors, including genetics, diet, age, and environmental factors, and often affect various...

Small Molecule Reactivator of p53 Y220C Mutant

Mutant p53 is one of the most attractive targets for new anti-cancer drugs. Although traditionally regarded as difficult to drug,...

BaF3 Models Carrying HER2 Mutations

Frequently observed in NSCLC patients, the 4 amino acid YVMA insertion is the most common type of HER2 exon 20...

Imiquimod-induced Psoriasis-like Dermatitis in NHP

Psoriasis is a chronic autoimmune skin disease characterized by abnormal keratinocyte proliferation and infiltration of inflammatory cells. The absence of...

NLRP3 Inhibitor Reverses Melanoma-Induced Vitiligo

Vitiligo is an autoimmune disorder characterized by the progressive destruction of melanocytes in the skin. This condition is driven by...

Animal Models of Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory condition that is mediated by genetic, immune, and environmental factors. Due...

Molecular Glues Discovery: Challenges and Opportunities

Introduction: Molecular glues (MGs) are a class of small molecules that alter the surface properties of proteins to strengthen or...

OncoWuXi Express: Pancreatitis Animal Models

OncoWuXi Express will continue to keep you informed about updates to our online tumor model database (OncoWuXi Database), as well...

PRMT5 Related Tumor Models

Homozygous deletion of methylthioadenosine phosphorylase (MTAP) in cancers such as glioblastoma represents a potentially targetable vulnerability. MTAP deletions occur in...

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