Knowledge Library

How Diversity In Therapeutic Strategies Is Expanding The Drug Discovery Toolbox

Resource Type: White Paper
Resource Topic: Antibody Drug Conjugate Oligonucleotides Oncology Rare Diseases Target Identification and Validation Targeted Protein Degradation THERAPEUTIC MODALITIES

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Targeted Protein Degradation Platform

Integrated Services BIOLOGY & PHARMACOLOGY BINARY/TERNARY COMPLEX FORMATION Biochemical & Biophysical Assays Biochemical binding assay Cellular Assays TARGET UBIQUITINATION & DEGRADATION In vitro Assays-Target ubiquitination Target degradation assay PK/PD Animal Disease Model Evaluation CHEMISTRY Specific virtual library design Compound synthesis Conjugation and all type of custom syntheses from milligram to kilogram scale Purification and analytical …Read More >

Resource Type: Brochure
Resource Topic: Biochemical Assays Biophysical Assays Cell-based Assays Discovery Chemistry Hit-to-Lead Lead Optimization Small Molecules Targeted Protein Degradation

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DEL Screening – DELight Handbook

DEL Screening | WuXi AppTec DELight Kit  Faster and Lighter Drug Discovery DELight kit containing 58 libraries and 10.8 billion compounds, buffers and a step-by-step online experimental manual. Drug developers perform affinity selection according to the manual and return the sample to WuXi AppTec upon completion.

Resource Type: Brochure
Resource Topic: Chemical Biology and Proteomics DNA-Encoded Library (DEL) Hit Finding Screening Libraries Small Molecules Target Identification and Validation Targeted Protein Degradation

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WuXi Oncology and Immuno-Oncology Services

Integrated Oncology and Immuno-oncology Platform to Enable Translational Science from Drug Discovery to Clinical Biomarker Oncology Services CRISPR/Cas9 Gene Editing In Vitro Assay and HTS Tumor models Tumor Cell Panel and Screening Immunology and Immuno-oncology Platform Clinical Biomarker Immunology Services Ligand-receptor binding assays Cellular functional assays Assays for innate immunity pathways: macrophage, MDSC, NK, DC, …Read More >

Resource Type: Brochure
Resource Topic: Antibodies Biochemical Assays Biomarkers Cell-based Assays Cells and Protein Science Chemical Biology and Proteomics Gene Therapies High-throughput screening (HTS) Hit-to-Lead Immunology in vitro biology in vivo Pharmacology Lead Optimization Oncology Screening Libraries Small Molecules Target Identification and Validation Target-Specific Assays Targeted Protein Degradation Tumor Models

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Resource Topics
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