Knowledge Library
Discovery and preclinical evaluations of GST-HG131, a novel HBV antigen inhibitor for the treatment of...
Chronic HBV infection (CHB) is a major contributor to liver-related deaths worldwide. The ultimate endpoint of CHB treatment is sustained HBV...
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Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro
The 3C-like protease (3CLpro) is an essential enzyme for the replication of SARS-CoV-2 and thus is a target for drug...
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Optimization and Mechanistic Investigations of Novel Allosteric Activators of PKG1α
WuXi AppTec scientists recently contributed to a research article in the Journal of Medicinal Chemistry describing the optimization of a...
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Large-scale synthesis of a Notum inhibitor employing a modified Sakai reaction as the key step
WuXi AppTec scientists recently contributed to a research article in the Royal Society of Chemistry describing the large-scale synthesis of...
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WuXi Biology Fact Sheet
Expertise in all major disease areas and all major target classes, enabling discovery for all therapeutic modalities World class antiviral...
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Ligand Finding and Chemistry Workflows for Targeted Protein Degradation
This webinar will focus on aspects related to PROTAC discovery and chemistry workflows, such as ligand finding strategies, synthesis optimization,...
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