DRUG DISCOVERY AND INNOVATION Archives - Page 2 of 6

Emerging Drug Discovery Strategies for Targeted Protein Degradation

In the last decade, targeted protein degradation (TPD) technology has become one of the most promising methods to remove specific...

Novel Approaches to Targeted Protein Degradation

In the last decade, targeted protein degradation (TPD) technology has become one of the most promising methods to remove specific...

Emerging Modalities in Drug Discovery

In this webinar, we present the latest advances and challenges facing researchers focused on new and emerging modalities in drug...

Discovery and preclinical profile of LX-039, a novel indole-based oral selective estrogen receptor degrader (SERD)

WuXi AppTec scientists contributed to a study which identified a novel, indole-based, selective estrogen receptor degrader (SERD), designated LX-039. The authors...

Inhibition of the hERG potassium ion channel by non-nucleoside CMV polymerase antiviral inhibitors

WuXi AppTec scientists collaborated on a study to characterize a series of pyrroloquinoline derivatives that were designed and synthesized to...

Recent Advances in Library Synthesis to Accelerate Medicinal Chemistry Research

Learn how parallel medicinal chemistry (PMC) and high-throughput experimentation (HTE) can provide a more focused approach to target molecules, resulting...

Research Chemistry Services

WuXi AppTec’s Research Chemistry Services (RCS) is a global leading chemistry platform offering synthetic and medicinal chemistry solutions to pharmaceutical...

Biophysical and Structural Biology Methods Enable Fragment-based Covalent Ligand Discovery of Human BTK

Drug Discovery Chemistry Conference 2023 Powerful biophysical and structural biology tools enable the study of large numbers of covalent fragments...

Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors

Dual leucine zipper kinase (DLK) and leucine zipper-bearing kinase (LZK) have emerged as key regulators of neuronal degeneration and axon...

Knowledge Library

Emerging Drug Discovery Strategies for Targeted Protein Degradation

Novel Approaches to Targeted Protein Degradation

Emerging Modalities in Drug Discovery

Discovery and preclinical profile of LX-039, a novel indole-based oral selective estrogen receptor degrader (SERD)

Inhibition of the hERG potassium ion channel by non-nucleoside CMV polymerase antiviral inhibitors

Recent Advances in Library Synthesis to Accelerate Medicinal Chemistry Research

Research Chemistry Services

Biophysical and Structural Biology Methods Enable Fragment-based Covalent Ligand Discovery of Human BTK

Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors

Contact An Expert Today!

Emerging Drug Discovery Strategies for Targeted Protein Degradation

Novel Approaches to Targeted Protein Degradation

Emerging Modalities in Drug Discovery

Discovery and preclinical profile of LX-039, a novel indole-based oral selective estrogen receptor degrader (SERD)﻿

Inhibition of the hERG potassium ion channel by non-nucleoside CMV polymerase antiviral inhibitors

Recent Advances in Library Synthesis to Accelerate Medicinal Chemistry Research

Research Chemistry Services

Biophysical and Structural Biology Methods Enable Fragment-based Covalent Ligand Discovery of Human BTK

Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors

Contact An Expert Today!

Discovery and preclinical profile of LX-039, a novel indole-based oral selective estrogen receptor degrader (SERD)