Discovery of a Specific CKIP-1 Ligand using DEL
Casein kinase 2-interacting protein-1 (CKIP-1) performs a critical negative role in the regulation of bone formation. Accumulated evidence strongly supports...
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Casein kinase 2-interacting protein-1 (CKIP-1) performs a critical negative role in the regulation of bone formation. Accumulated evidence strongly supports...
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The heme oxygenase (HO) family comprises the major isozymes HO-1 and HO-2, of which HO-1 is deemed as an emerging...
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The safe production of cultivated plants is threatened by various fungal diseases. NIS1 is a secreted effector protein produced by...
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Casitas B lymphoma-b (Cbl-b), a RING finger E3 ubiquitin ligase, is a key regulator of T cell activation and plays...
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In the last decade, targeted protein degradation (TPD) technology has become one of the most promising methods to remove specific...
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WuXi AppTec offers a comprehensive platform of in silico drug discovery services to accelerate the process of hit finding and...
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In addition to identifying chemical starting points for early drug discovery processes, DNA-encoded library (DEL) technology has now expanded to...
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Despite the availability of modern screening technologies, identification and optimization of hits against poorly druggable targets remains a significant challenge...
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WuXi AppTec scientists published a study in the open access archive ChemRxiv describing the discovery of highly selective, novel, heme...
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