We offer an extensive panel of cutting-edge immune profiling and biomarker discovery services to support: Target discovery and validation Drug efficacy assessment Mechanism of action and PD studies Identification of predictive biomarkers, to support patient stratification Check out our comprehensive platform of immunology services View our panel of biomarker and immune profiling services

Multidisciplinary testing platforms that enable support to detect, develop, and validate biomarkers of cancer. End-to-end services in pathology, flow cytometry, and molecular biology techniques Rigorous quality management system, and well-established sample and data management procedures Multi-omics analysis utilizing multidisciplinary testing platforms CAP-accredited clinical biomarker lab has been established since 2015 View our comprehensive platform of …Read More >

Pilot Studies (selection of optimal time points and dosing) In vivo treatment Sample collection (from complex tissue to single cell isolation) Library preparation and sequencing Bioinformatics analysis View our cutting-edge immune profiling and biomarker platforms

Dual leucine zipper kinase (DLK) and leucine zipper-bearing kinase (LZK) have emerged as key regulators of neuronal degeneration and axon growth.  WuXi AppTec scientists recently contributed to a research article in the Journal of Medicinal Chemistry demonstrating the use of ligand- and structure-based drug design approaches to discover an amino-pyrazine chemical series of DLK and …Read More >

Offering a comprehensive platform of in vitro imaging-based assays to screen compounds for cancer, inflammation, and autoimmune diseases. Our services include: Imaging assays for cell proliferation and apoptosis Imaging assays for cell cycle analysis Cell-based functional assays, including: Antibody internalization Live-cell immunocytochemistry Cellular movement and morphology monitoring Assays for 3D cell models, including: Spheroid growth …Read More >

Neurological disorders, such as neurodegenerative diseases, epilepsy, chronic pain, psychiatric disorders, are one of today’s largest unmet medical needs. However, due to poor disease and target understanding, Neuroscience drug discovery can be very challenging. An open access research platform with dedicated neuroscience specialists and integrated services will be an ideal partner throughout your drug discovery …Read More >

Nucleic acids have long been regarded as biological compounds for storing and transferring information. However, their functionalities are far more diverse than this – ranging from gene regulation to enzymatic catalysis. One type of unconventional nucleic acid is the aptamer. Aptamers are short, single stranded nucleic acids that fold into highly specific structures. They bind …Read More >