Knowledge Library
Novel Peptide Hit Identification and Lead Generating Strategies for Drug Discovery
Recent Advances in Library Synthesis to Accelerate Medicinal Chemistry Research
Enabling Drug Discovery with Diverse Lead Generation Platforms
Optimizing Drug Discovery Pipelines with Biophysical Methods
Discovery of RNA binding molecule using DNA-encoded library technology
Novel Strategies to Accelerate Discovery of Translatable Therapeutic Targets
Quantitative Histopathology of Fibrosis in an Animal Model of NASH
The hepatic fibrosis has been the most challenging aspect in the animal models for nonalcoholic steatohepatitis (NASH). Although it could induced by nutritional (high-fat died with high cholesterol, methionine and choline deficient diet, etc), chemical (carbon tetrachloride, thioacetamide, α-naphthylisothiocyanate etc.), and surgical (bile duct ligation) means, the clinical relevance of the resulting fibrosis remains an …Read More >
Aug 2021: Wuxi AppTec immune profiling in drug discovery and CLDN18.2-related tumor models.
Validation of GVHD in mouse model for preclinical efficacy screen
AACR Annual meeting 2021 Na Xu, Ya Zhang, Rou Xie, Lijun Jia, Yingying Cai, Qing Lin Oncology and Immunology Unit, WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China Background Bone marrow transplantation has been successfully and widely used to treat diseases such as leukemia and lymphomas. However, the complication Graft …Read More >
