Knowledge Library

HIJACKING CELLULAR MECHANISMS TO TREAT COMPLEX DISEASES

Resource Type: White Paper
Resource Topic: Biochemical Assays Biomarkers Biophysical Assays Cell-based Assays DRUG DISCOVERY AND INNOVATION in vitro biology Oligonucleotides Oncology Rare Diseases Target Identification and Validation Target-Specific Assays Targeted Protein Degradation

VIEW

RARE DISEASES: OPPORTUNITIES AND CHALLENGES FOR TREATMENTS DELIVERED BY ADENO-ASSOCIATED VIRUSES

Resource Type: White Paper
Resource Topic: Biomarkers Gene Therapies in vivo Pharmacology Rare Diseases Target Identification and Validation

VIEW

Meeting Neurodegenerative Disease Head-On with Emerging Drug Discovery Strategies

Chronic neurodegenerative diseases encompass a variety of progressive conditions that affect neurons, including Huntington’s disease, Parkinson’s disease, Alzheimer’s disease, and other forms of dementia. They are among the most common and challenging central nervous system (CNS) diseases. “Many companies had stopped their research program into neurodegenerative diseases, but now sophisticated technology advances have became more broadly …Read More >

Resource Type: Presentation White Paper
Resource Topic: Biomarkers Cell-based Assays Central Nervous System & Pain Chemical Biology and Proteomics Hit-to-Lead in silico services in vivo Pharmacology Lead Optimization Rare Diseases

VIEW

WuXi Discovery Services Newsletter: November 2021

Resource Type: Newsletter
Resource Topic: Biophysical Assays Central Nervous System & Pain Oligonucleotides Rare Diseases Targeted Protein Degradation

VIEW

WuXi Discovery Services Newsletter: October 2021

Resource Type: Newsletter
Resource Topic: Central Nervous System & Pain Mass Spectrometry-based Assays Quantum Mechanics Rare Diseases

VIEW

How Diversity In Therapeutic Strategies Is Expanding The Drug Discovery Toolbox

Resource Type: White Paper
Resource Topic: Antibody Drug Conjugate Oligonucleotides Oncology Rare Diseases Target Identification and Validation Targeted Protein Degradation THERAPEUTIC MODALITIES

VIEW

Identification of Tofacitinib, Filgotinib and Ruxolitinib on experimental Sjögren’s syndrome model in mice

Sjögren’s syndrome, which affects hundreds of millions of people worldwide, is a chronic autoimmune disorder characterized by leukocytic infiltration into the exocrine glands, such as the salivary and lacrimal glands. However, the pathological mechanism remains to be elucidated, and novel treatments are urgently needed. Over the past decade, extensive progress has been made in the …Read More >

Resource Type: Poster
Resource Topic: Autoimmune and Inflammatory Diseases in vivo Pharmacology Lead Optimization Rare Diseases Small Molecules Structural Biology

VIEW


Resource Topics
× peptide, amino acid

Contact An Expert Today!