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WuXi AppTec Discovery Services

Delivering comprehensive end-to-end solutions for creating, identifying, and supporting preclinical candidates, from discovery to development, with our integrated chemistry and biology research platforms.  
Resource Type: Brochure
Resource Topic: Antibodies, Antibody Drug Conjugate, Autoimmune and Inflammatory Diseases, Biochemical Assays, Biomarkers, Biophysical Assays, Candidate Selection, CAR-T Cell, Cardiovascular & Metabolic Diseases, Cell Therapies, Cell-based Assays, Cells and Protein Science, Central Nervous System & Pain, Chemical Biology and Proteomics, Dermatology, Discovery Chemistry, DNA-Encoded Library (DEL), DRUG DISCOVERY AND INNOVATION, Fragment-Based Drug Discovery, Gene Therapies, High-throughput screening (HTS), Hit Finding, Hit-to-Lead, Immunology, in silico services, in vitro biology, in vivo Pharmacology, in vivo Toxicology, Infectious Diseases, Lead Optimization, Liver Diseases, Mass Spectrometry-based Assays, Metabolic Diseases, NASH, Oligonucleotides, Oncology, Oncolytic Viruses, Ophthalmology, Phenotypic Assays, Quantum Mechanics, Rare Diseases, Respiratory Diseases, Safety and Early Toxicity, Screening Libraries, Screening Services, Small Molecules, Structural Biology, Target Identification and Validation, Target-Specific Assays, Targeted Protein Degradation, TECHNOLOGY PLATFORMS, THERAPEUTIC AREAS, THERAPEUTIC MODALITIES, Tumor Models

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HIJACKING CELLULAR MECHANISMS TO TREAT COMPLEX DISEASES
Resource Type: White Paper
Resource Topic: Biochemical Assays, Biomarkers, Biophysical Assays, Cell-based Assays, DRUG DISCOVERY AND INNOVATION, in vitro biology, Oligonucleotides, Oncology, Rare Diseases, Target Identification and Validation, Target-Specific Assays, Targeted Protein Degradation

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RARE DISEASES: OPPORTUNITIES AND CHALLENGES FOR TREATMENTS DELIVERED BY ADENO-ASSOCIATED VIRUSES
Resource Type: White Paper
Resource Topic: Biomarkers, Gene Therapies, in vivo Pharmacology, Rare Diseases, Target Identification and Validation

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Meeting Neurodegenerative Disease Head-On with Emerging Drug Discovery Strategies

Chronic neurodegenerative diseases encompass a variety of progressive conditions that affect neurons, including Huntington’s disease, Parkinson’s disease, Alzheimer’s disease, and other forms of dementia. They are among the most common and challenging central nervous system (CNS) diseases. “Many companies had stopped their research program into neurodegenerative diseases, but now sophisticated technology advances have became more broadly …Read More >
Resource Type: Presentation, White Paper
Resource Topic: Biomarkers, Cell-based Assays, Central Nervous System & Pain, Chemical Biology and Proteomics, Hit-to-Lead, in silico services, in vivo Pharmacology, Lead Optimization, Rare Diseases

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WuXi Discovery Services Newsletter: November 2021
Resource Type: Newsletter
Resource Topic: Biophysical Assays, Central Nervous System & Pain, Oligonucleotides, Rare Diseases, Targeted Protein Degradation

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WuXi Discovery Services Newsletter: October 2021
Resource Type: Newsletter
Resource Topic: Central Nervous System & Pain, Mass Spectrometry-based Assays, Quantum Mechanics, Rare Diseases

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How Diversity In Therapeutic Strategies Is Expanding The Drug Discovery Toolbox
Resource Type: White Paper
Resource Topic: Antibody Drug Conjugate, Oligonucleotides, Oncology, Rare Diseases, Target Identification and Validation, Targeted Protein Degradation, THERAPEUTIC MODALITIES

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Identification of Tofacitinib, Filgotinib and Ruxolitinib on experimental Sjögren’s syndrome model in mice

Sjögren’s syndrome, which affects hundreds of millions of people worldwide, is a chronic autoimmune disorder characterized by leukocytic infiltration into the exocrine glands, such as the salivary and lacrimal glands. However, the pathological mechanism remains to be elucidated, and novel treatments are urgently needed. Over the past decade, extensive progress has been made in the …Read More >
Resource Type: Poster
Resource Topic: Autoimmune and Inflammatory Diseases, in vivo Pharmacology, Lead Optimization, Rare Diseases, Small Molecules, Structural Biology

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Resource Topics
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