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Resource Type: Presentation Video
Resource Topic: Biochemical Assays Biophysical Assays Cell-based Assays Target Identification and Validation Targeted Protein Degradation

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Immuno-Oncology Platform to Enable Discovery from Target to Drug
Resource Type: Presentation Video
Resource Topic: Biomarkers Cell-based Assays Cells and Protein Science DRUG DISCOVERY AND INNOVATION Hit Finding Hit-to-Lead Lead Optimization Oncology Screening Libraries Target Identification and Validation Tumor Models

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Enabling Technologies for Targeted Protein Degradation Webinar
Resource Type: Webinar
Resource Topic: Biochemical Assays Biophysical Assays Cell-based Assays Discovery Chemistry Small Molecules Target Identification and Validation Target-Specific Assays Targeted Protein Degradation

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Enabling Technologies For Bifunctional Molecule Discovery And Characterization
Resource Type: Webinar
Resource Topic: Biochemical Assays Biophysical Assays Cell-based Assays Discovery Chemistry Small Molecules Structural Biology Target Identification and Validation Target-Specific Assays Targeted Protein Degradation

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Cancer Immunotherapy and the Application of In Vitro Immunoassays in Drug Development
Resource Type: Webinar
Resource Topic: Antibodies Autoimmune and Inflammatory Diseases Biochemical Assays Cell-based Assays Hit-to-Lead Immunology Lead Optimization Oncology Phenotypic Assays Small Molecules Target Identification and Validation Target-Specific Assays

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Optimizing Drug Discovery Pipelines with Biophysical Methods
Resource Type: Webinar
Resource Topic: Antibodies Biochemical Assays Biomarkers Biophysical Assays Cell-based Assays DNA-Encoded Library (DEL) Fragment-Based Drug Discovery Hit Finding Hit-to-Lead Mass Spectrometry-based Assays Oncology Phenotypic Assays Screening Libraries Small Molecules Structural Biology Target Identification and Validation Target-Specific Assays Targeted Protein Degradation

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Aug 2021: Wuxi AppTec immune profiling in drug discovery and CLDN18.2-related tumor models.
Resource Type: Newsletter
Resource Topic: Candidate Selection Cell-based Assays Hit-to-Lead Immunology Lead Optimization Oncology Tumor Models

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Validation of GVHD in mouse model for preclinical efficacy screen

AACR Annual meeting 2021 Na Xu, Ya Zhang, Rou Xie, Lijun Jia, Yingying Cai, Qing Lin Oncology and Immunology Unit, WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China Background Bone marrow transplantation has been successfully and widely used to treat diseases such as leukemia and lymphomas. However, the complication Graft …Read More >
Resource Type: Poster
Resource Topic: Biochemical Assays Biomarkers Cell-based Assays Cells and Protein Science Chemical Biology and Proteomics in vivo Pharmacology Oncology Tumor Models

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Engineered cell line panel complemented with in vivo models to enable next-generation target therapy discovery in cancer

 AACR Annual meeting 2021   Authors: Zhixiang Zhang1, Feifei Fan2, Xiaohe Shi2, Xiangyang Zuo2, Qingyang Gu2, Qunsheng Ji1. 1 WuXi AppTec, Shanghai, China; 2 WuXi AppTec, Jiangsu, China Corresponding Author: Qunsheng Ji. Email: ji_qunsheng@wuxiapptec.com   Background  Many cancer types are driven by specific gene aberrances, like gene fusions, mutations and copy number changes. It has led to …Read More >
Resource Type: Poster
Resource Topic: Biomarkers Cell-based Assays Oncology Phenotypic Assays Target Identification and Validation Tumor Models

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