Induced Pruritus Model in NHP
The “itch-scratch cycle” is a central pathogenic driver in many pruritic (itch-related) inflammatory skin diseases, such as atopic dermatitis (AD),...
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The “itch-scratch cycle” is a central pathogenic driver in many pruritic (itch-related) inflammatory skin diseases, such as atopic dermatitis (AD),...
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Spontaneous mouse tumor-derived syngeneic models are valuable tools in preclinical cancer research. These tumor models offer unique advantages because immunotherapies...
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T-cell engagers (TCEs) are a class of bispecific antibody-based immunotherapies designed to bring T cells into close proximity with cancer...
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Metabolic dysfunction-associated steatohepatitis (MASH), previously known as nonalcoholic steatohepatitis (NASH), is a serious liver disease. If left untreated, MASH can...
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Systemic lupus erythematosus (SLE) is a serious, chronic autoimmune disorder characterized by a heterogeneous clinical presentation, in which various organs...
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Systemic sclerosis (also known as scleroderma) is a chronic autoimmune disease that leads to the buildup of scar tissue in...
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Synthetic lethality, where combining two non-lethal mutations results in cell death, is exploited in cancer therapy, with PARP inhibitors like...
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Polycythemia vera (PV) is a chronic myeloproliferative disorder, a type of blood cancer characterized by the overproduction of red blood...
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Epilepsy is a chronic brain disorder characterized by recurring seizures, which are episodes of uncontrolled and abnormal electrical activity in...
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