Development of NK Humanized Mouse Models
Natural killer (NK) cells play a crucial role in the immune system and can recognize and kill cancer cells. Research...
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Isogeneic Trop-2 Model for Evaluating Anti-Trop-2 ADCs
Antibody-Drug Conjugates (ADCs) have made significant advancements in cancer treatment, particularly for solid tumors. The bystander effect of ADCs, where...
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HPV18-Related Cancer Model Development
Cancers, like cervical cancer and head & neck cancer, are strongly linked to human papillomavirus (HPV) infection. Targeting the HPV...
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Development of Novel ADC-Resistant Models
Antibody‒drug conjugates (ADCs), which combine the advantages of monoclonal antibodies with precise targeting and payloads, show great potential as cancer...
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DNA-Compatible Huisgen Cycloaddition
In our latest publication, WuXi AppTec scientists introduce two new methods that utilize readily accessible aldehydes to create substituted isoxazolines...
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