Knowledge Library
Drugging the Undruggable: Leveraging the Right Screening Methods for Challenging Targets
Challenging targets, such as membrane proteins or protein-protein interactions were considered undruggable in the past. However, today a variety of screening methods can be used to help develop drugs against these formerly undruggable targets.
Resource Type: Infographic
Resource Topic: DNA-Encoded Library (DEL), Hit Finding, in silico services, Mass Spectrometry-based Assays, Screening Services, Small Molecules, Structural Biology, Target Identification and Validation, Targeted Protein Degradation
Structure determination: comparison of methods
WuXi AppTec offers comprehensive structural generation solutions for today´s challenging targets. Our experts provide insights and data to support hit finding through to lead optimization.
Resource Type: Brochure, Infographic
Resource Topic: Biophysical Assays, Cells and Protein Science, Hit Finding, Hit-to-Lead, Lead Optimization, Structural Biology, Target Identification and Validation
