Research Strategies for the Discovery of Targeted Protein Degraders

In this webinar, experts present research strategies for the discovery of targeted protein degraders. Over the past decade, targeted protein degradation (TPD) technology has become one of the most promising methods to remove specific disease-related proteins using cellular self-destruction mechanisms.

Since 2016, WuXi AppTec has built a comprehensive TPD discovery service platform, adept in over 20 assay formats to investigate the full TPD functional cycle from binary/ternary complex formation and protein ubiquitination to degradation. Our broad and deep expertise also includes advanced screening techniques for hit identification, and custom synthesis and purification of new linkers and E3 ligase ligands.