Resources Archive - Page 18 of 52

Streamlining Gene Therapy with AAVs

Gene therapies are enabling a rapid expansion in the scope of treatable disease. Adeno-associated viruses (AAVs) are particularly advantageous delivery...

Developing Novel AR Mutant Prostate Cancer Models

Since prostate cancer heavily depends on androgen hormones for growth, targeting the androgen receptor (AR) signaling pathway is a key...

Toxicology Profile of a Novel GLP-1 Receptor Agonist

Glucagon‐like peptide‐1 (GLP-1) receptor agonists have emerged as promising therapeutic options for addressing type‐2 diabetes, obesity, and related conditions. However,...

Strategies for Screening and Characterizing Targeted Covalent Inhibitors

With advancements in drug design, there is resurging interest in drugs that form covalent bonds with their targets, often referred...

Discovery of a Specific CKIP-1 Ligand using DEL

Casein kinase 2-interacting protein-1 (CKIP-1) performs a critical negative role in the regulation of bone formation. Accumulated evidence strongly supports...

Application of Affinity Selection Mass Spectrometry: Membrane Proteins

Introduction Membrane proteins are essential for various cellular processes, including energy conversion, signal transduction, and disease progression. Efficient and accurate...

Animal Disease Models of Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a prevalent, chronic, autoimmune disease. The onset and progression of RA are closely associated with an...

Application of Affinity Selection Mass Spectrometry: Molecular Glues Drug Discovery

Introduction: New modalities, such as molecular glues, require robust screening strategies to identify and develop the most promising candidates efficiently....

OncoWuXi Express: Anti-Tumor mRNA Drugs

OncoWuXi Express will continue to keep you informed about updates to our online tumor model database (OncoWuXi Database), as well...

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