Asthma Services Platform

Asthma is a chronic, lower airway disease characterized by persistent inflammation and hyperreactivity. Asthma involves a complex immune response, with T-helper 2 (Th2) cells playing a central role, leading to activation of eosinophils and increased levels of IgE antibodies. Clinically, airflow obstruction in asthma often is not fully reversible, and many asthmatic subjects experience an accelerated and progressive loss of lung function over time.

To support drug discovery teams focused on asthma research, WuXi AppTec offers a comprehensive panel of in vitro assays and in vivo animal models.  Our platform includes OVA-induced and HDM-induced mouse asthma models, as well as TSLP, IL-33, and IL-4/IL-13 signaling inhibition assays, a Th2 cell chemotaxis assay, and a mast cell degranulation assay.

Comprehensive Preclinical Evaluation Platform for Asthma Disease

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