Phage Display

Conventional phage display enables rapid, cost-effective, and scalable peptide discovery, enriching high-affinity binders with easy sequencing. WuXi Biology phage display offers diverse screening strategies and can display structurally complex peptides.

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Features

  • Natural amino acids dominate
  • Compatible with cellular selection and in vivo selection
  • Panning format:  Protein based panning (Protein captured by beads or coated on the surface of tube), cell based panning

Off-The-Shelf Peptide Phage Libraries

WuXi provides Off-The-Shelf Peptide Phage Libraries with flexible length

  • 5 monocyclic peptide libraries (15 AA)
  • 3 linear peptide libraries (9 AA, 12 AA, 30 AA)

Average diversity: 8E+09

Average diversity: 4E+09

Customized Peptide Phage Libraries

Codons can also be optimized for customized library based on two strategies for oligonucleotide synthesis. WuXi Biology  has the ability of the whole workflow of phage library construction from pilot test of ligation and transfection to large scale ligation and transfection for library construction.

Phage-Display Panning and Screening Workflow

WuXi Biology provides panning services and hits validation. In addition to conventional ELISA, we have newly introduced a high-throughput sequencing-based approach to final more candidates.