DELvision: A Protein-DEL Interaction Database

Currently, there is a lack of efficient experimental strategies to collect high-quality proteome-level data for protein-ligand interactions (PLIs).  At DEL Symposium 2025 in Boston, WuXi AppTec presented a poster showcasing our advanced DELvision database, representing the first use of DNA-encoded library (DEL) technology for establishing a protein-DEL interaction database.

The authors demonstrate how DEL can be applied for profiling vast small molecule chemical spaces for their binding capabilities with thousands of proteins.  In this manner, the DELvision database can help bridge the gap between a large chemical space and the druggable genome.

Poster_DELvision_2025 DEL Symposium

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