Targeted Protein Degraders: Trends, Challenges, and Solutions
Since 2016, WuXi AppTec has built a comprehensive discovery platform focused on Targeted Protein Degraders (TPDs). Our platform enables research teams to investigate the complete TPD functional cycle, from binary and ternary complex formation to protein ubiquitination and degradation. Our end-to-end services encompass over 20 assay technologies, 10+ types of TPD molecules, and one-stop screening for proteins of interest (POI) and linkers using a bifunctional DNA-encoded library.
Our seamless partnership with WuXi Chemistry enables us to deliver all-encompassing solutions that leverage chemistry, structural biology, target validation, in vitro pharmacology, in vivo evaluation, and biomarker analysis.
Related Content
DNA-encoded library (DEL) technology has been recognized as a major screening method, offering unique advantages through its ability to provide...
VIEW RESOURCEIn this webinar, WuXi Biology scientists showcase our end-to-end molecular glue discovery platform. Molecular glues act as "molecular adhesives”, facilitating...
VIEW RESOURCE