Fluoroalkane modified cationic polymers for personalized mRNA cancer vaccines
Delivery carriers are a critical component in the development of mRNA vaccines. Here, we describe the synthesis of a cationic polymer as a carrier for mRNA cancer vaccine delivery. In vivo results show that this polymer-based mRNA vaccine significantly delays tumor growth after vaccination of mice.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743697/
Fluoroalkane modified cationic polymers for personalized mRNA cancer vaccine-CEJ 2023 Jan
Related Content
Rat tumor models are a better mimic of human pathology compared to mice. The tumor stroma component of rats is...
VIEW RESOURCEThe efficacy of CAR-T therapy is substantially influenced by the tumor microenvironment. This is particularly evident when PD-L1 is activated...
VIEW RESOURCE