Oligonucleotide Drug Discovery

Recent years have seen a huge surge of interest in oligonucleotide therapeutics, fueled by major advances in our understanding of how to make such molecules stable, selective, and efficient as drug modalities. The field is now diverse in terms of therapeutic areas being addressed, biological processes being manipulated and delivery technologies employed.

In this webinar, with experts involved in providing state of the art technical support to the discovery stages of an oligonucleotide therapeutic programme, we discussed the synthesis and modification of oligonucleotides, design and execution of suitable in vitro and in vivo assays, and methods for determining pharmacokinetic parameters.

By viewing this webinar session, you will also hear about state of the art discovery strategies with a case history from an exciting young biotech company employing oligonucleotides to create impactful therapeutics.